YUHSpace: Fang, Sungsoon
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Browsing by Yonsei Author : Fang, Sungsoon
Name :
Fang, Sungsoon [황성순]
http://orcid.org/0000-0003-0201-5567
Department :
College of Medicine (의과대학) - BioMedical Science Institute (의생명과학부)
Scopus ID :
(7402422501)
Medical Student Research Advisor
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세포 에너지대사 연구
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sfang@yuhs.ac
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세포 에너지대사 연구실 (Fang Lab)
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ABMRC 418호
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Wet Lab (50%), Dry Lab (50%)
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연구 내용
다양한 병리적 상황에서 나타나는 세포의 에너지 대사기전을 확인하고, 세포가 생존하는 신호체계를 확인함으로써 질환을 치료할 수 있는 신규 치료 타겟을 발굴함
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- Public data를 기반으로 환자 임상 데이터 분석 기법 탐구 (R studio/Python)
- RNA 및 DNA 기반 유전체 분석 기법
- Tumoroid 배양 기법
- 다양한 분자생물학 기법
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- R studio, Python
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Showing results 1 to 50 of 52
Articles
(52)
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Issue Date
Title
Journal Title
2025
One-carbon metabolic pathway is a novel molecular signature for CD44-positive intestinal-type gastric cancer
CELL DEATH DISCOVERY
2025
Novel mechanism whereby metformin improves glucose homeostasis: TXNIP-GLUT1 axis modulation enhances intestinal glucotonic effects
EXPERIMENTAL AND MOLECULAR MEDICINE
2025
Exercise alters transcriptional profiles of senescence and gut barrier integrity in intestinal crypts of aging mice
NPJ AGING
2025
Dynamics of T Cell-Mediated Immune Signaling Network During Pathogenesis of Chronic Obstructive Pulmonary Disease
YONSEI MEDICAL JOURNAL
2025
Reply to correspondence 2 on "GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers
CLINICAL AND MOLECULAR HEPATOLOGY
2025
The FOXP1-ABCG2 axis promotes the proliferation of cancer stem cells and induces chemoresistance in pancreatic cancer
CANCER GENE THERAPY
2025
Bridging the gap: The GOLM1-OPN-ABCG5 axis in MASH and gallstone disease: Editorial on "GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers"
CLINICAL AND MOLECULAR HEPATOLOGY
2025
One-carbon metabolism is distinct metabolic signature for proliferative intermediate exhausted T cells of ICB-resistant cancer patients
CELL DEATH DISCOVERY
2024
Inhibition of HTR2B-mediated serotonin signaling in colorectal cancer suppresses tumor growth through ERK signaling
BIOMEDICINE & PHARMACOTHERAPY
2024
PHGDH: a novel therapeutic target in cancer
EXPERIMENTAL AND MOLECULAR MEDICINE
2024
Bile Acids and Gastric Intestinal Metaplasia: Exploring a New Feedback Loop
GUT AND LIVER
2024
DGAT2 Plays a Crucial Role to Control ESRRAPROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability
DIABETES & METABOLISM JOURNAL
2024
Triamcinolone acetonide alleviates benign biliary stricture by ameliorating biliary fibrosis and inflammation
BMB REPORTS
2024
BRCA1 mutation promotes sprouting angiogenesis in inflammatory cancer-associated fibroblast of triple-negative breast cancer
CELL DEATH DISCOVERY
2023
Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer
CANCER BIOLOGY & THERAPY
2023
Fat Biology in Triple-Negative Breast Cancer: Immune Regulation, Fibrosis, and Senescence
JOURNAL OF OBESITY & METABOLIC SYNDROME
2023
Creeping fat exhibits distinct Inflammation-specific adipogenic preadipocytes in Crohn's disease
FRONTIERS IN IMMUNOLOGY
2023
Caveolin-1 mediates the utilization of extracellular proteins for survival in refractory gastric cancer
EXPERIMENTAL AND MOLECULAR MEDICINE
2023
CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice
DIABETES & METABOLISM JOURNAL
2023
Gene signature from cutaneous autoimmune diseases provides potential immunotherapy-relevant biomarkers in melanoma
SCIENTIFIC REPORTS
2023
CD74 Promotes a Pro-Inflammatory Tumor Microenvironment by Inducing S100A8 and S100A9 Secretion in Pancreatic Cancer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2023
Co-inhibition of glutaminolysis and one-carbon metabolism promotes ROS accumulation leading to enhancement of chemotherapeutic efficacy in anaplastic thyroid cancer
CELL DEATH & DISEASE
2023
Inhibition of protein arginine deiminase II suppresses retinoblastoma in orthotopic transplantation in mice
ONCOLOGY REPORTS
2023
Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination
SCIENTIFIC REPORTS
2023
PHGDH preserves one-carbon cycle to confer metabolic plasticity in chemoresistant gastric cancer during nutrient stress
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2023
PMCA inhibition reverses drug resistance in clinically refractory cancer patient-derived models
BMC MEDICINE
2022
Bifidobacterial carbohydrate/nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet-induced obesity
MICROBIOME
2022
The Peripheral Immune Landscape in a Patient with Myocarditis after the Administration of BNT162b2 mRNA Vaccine
MOLECULES AND CELLS
2022
Single-cell sequencing of PBMC characterizes the altered transcriptomic landscape of classical monocytes in BNT162b2-induced myocarditis
FRONTIERS IN IMMUNOLOGY
2022
Gut Epithelial Inositol Polyphosphate Multikinase Alleviates Experimental Colitis via Governing Tuft Cell Homeostasis
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY
2022
Ivermectin and gemcitabine combination treatment induces apoptosis of pancreatic cancer cells via mitochondrial dysfunction
FRONTIERS IN PHARMACOLOGY
2022
Discovery of ( E)-3-(3-((2-Cyano-4'-dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis
JOURNAL OF MEDICINAL CHEMISTRY
2022
Preclinical evaluation of endoscopic placement of a steroid-eluting metal stent in an in vivo porcine benign biliary stricture model
SCIENTIFIC REPORTS
2022
Effects of Anti-Cancer Drug Sensitivity-Related Genetic Differences on Therapeutic Approaches in Refractory Papillary Thyroid Cancer
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Therapeutic Strategies for Diabetes: Immune Modulation in Pancreatic β Cells
FRONTIERS IN ENDOCRINOLOGY
2021
Sp1-Induced FNBP1 Drives Rigorous 3D Cell Motility in EMT-Type Gastric Cancer Cells
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2021
Bifidobacterium Strain-Specific Enhances the Efficacy of Cancer Therapeutics in Tumor-Bearing Mice
CANCERS
2020
Lactobacillus fermentum promotes adipose tissue oxidative phosphorylation to protect against diet-induced obesity
EXPERIMENTAL AND MOLECULAR MEDICINE
2020
Dexras1 plays a pivotal role in maintaining the equilibrium between adipogenesis and osteogenesis
METABOLISM-CLINICAL AND EXPERIMENTAL
2020
GPx7 ameliorates non-alcoholic steatohepatitis by regulating oxidative stress
BMB REPORTS
2020
ID1-Mediated BMP Signaling Pathway Potentiates Glucagon-Like Peptide-1 Secretion in Response to Nutrient Replenishment
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2020
Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2019
Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes
MEDICINE
2019
RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2019
Combination treatment with n-3 polyunsaturated fatty acids and ursodeoxycholic acid dissolves cholesterol gallstones in mice
Scientific Reports
2019
Anti-obesity effect of taurine through inhibition of adipogenesis in white fat tissue but not in brown fat tissue in a high-fat diet-induced obese mouse model
Amino Acids
2019
FXR Regulates Intestinal Cancer Stem Cell Proliferation
CELL
2018
Crosstalk between FXR and TGR5 controls glucagon-like peptide 1 secretion to maintain glycemic homeostasis
Laboratory Animal Research
2018
Mouse Cre-LoxP system: general principles to determine tissue-specific roles of target genes
Laboratory Animal Research
2017
RORα2 requires LSD1 to enhance tumor progression in breast cancer
SCIENTIFIC REPORTS
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