Browsing by Yonsei Author

Name:
이민구 [Lee, Min Goo]
Department :
College of Medicine : Dept. of Pharmacology
Y-HRN :
(Yonsei Health Research Network)
This table browses all dspace content
Issue DateTitleYonsei Author(s)
2018Neopepsee: accurate genome-level prediction of neoantigens by harnessing sequence and amino acid immunogenicity information김상우, 김한상, 백순명, 이민구
2018ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms 김혜연, 노신혜, 이민구, 지헌영, 한수민
2018Unconventional protein secretion - new insights into the pathogenesis and therapeutic targets of human diseases이민구, 지헌영
2018Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth 김한상, 김형범, 백순명, 송재진, 육종인, 이민구, 차용훈, 최은창
2018Unconventional secretion of transmembrane proteins이민구, 지헌영
2018Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR강정민, 김연정, 노신혜, 이민구, 지헌영
2018Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2.김주영, 이민구
2018NPP1 is responsible for potent extracellular ATP hydrolysis as NTPDase1 in primary cultured murine microglia 김주영, 이민구
2017Sustained Mutant KIT Activation in the Golgi Complex Is Mediated by PKC-θ in Gastrointestinal Stromal Tumors김원규, 김지윤, 김호근, 이민구
2017Sec16A is critical for both conventional and unconventional secretion of CFTR 김주영, 김지윤, 노신혜, 박학, 이민구
2017Targeted Next-Generation Sequencing for Comprehensive Genetic Profiling of Pharmacogenes박준희, 이민구, 한수민
2017Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice이민구
2017UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1-/- Microglia In Vitro and In Vivo 김주영, 이민구
2017Comparison of clinical outcomes between wavefront-optimized versus corneal wavefront-guided transepithelial photorefractive keratectomy for myopic astigmatism김응권, 김태임, 서경률, 이민구, 전익현
2017Adult-Onset Vitelliform Macular Dystrophy caused by BEST1 p.Ile38Ser Mutation is a Mild Form of Best Vitelliform Macular Dystrophy 김응권, 이민구, 이승규, 이지환, 전익현, 지헌영, 최승일
2017A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD김원호, 김한상, 박수정, 박준희, 이민구, 정은석, 천재희
2017Chronological Change of Right Ventricle by Chronic Intermittent Hypoxia in Mice김주영, 김창훈, 윤주헌, 이민구, 조형주, 한정우
2017ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer박형순, 이민구, 전익현, 정진세, 정희철, 지헌영
2016Clinical and Pathological Heterogeneity of Korean Patients with CAPN3 Mutations 김승민, 신하영, 이민구, 이정환, 조성래, 최영철
2016Pharmacogenetic analysis of advanced non-small-cell lung cancer patients treated with first-line paclitaxel and carboplatin chemotherapy김주항, 김혜련, 박형순, 이민구, 조병철, 조응혁
2016The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for unconventional protein secretion. 김지윤, 노신혜, 이민구, 전익현, 정진세, 지헌영, 최재영
2016Mutations in SLC26A1 Cause Nephrolithiasis.이민구, 전익현, 지헌영
2016Pore dilatation increases the bicarbonate permeability of CFTR, ANO1 and glycine receptor anion channels.김연정, 김철훈, 박경수, 손한길, 윤주헌, 이민구, 전익현, 정진세
2016Prognostic Scoring Index for Patients with Metastatic Pancreatic Adenocarcinoma. 박준성, 박형순, 윤동섭, 이동기, 이민구, 이세준, 정희철
2016SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages김영삼, 김창훈, 류재찬, 배수한, 유지환, 윤주헌, 이민구, 이서구
2016Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR김동희, 김주영, 김지윤, 노신혜, 이민구
2016HLA-C*01 is a Risk Factor for Crohn's Disease김원호, 김태일, 박수정, 이민구, 정은석, 천재희, 홍성필
2016Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice김주영, 이민구, 이영호
2016Generation of ΔF508-CFTR T84 cell lines by CRISPR/Cas9-mediated genome editing김주영, 김형범, 이민구
2016Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus 김상우, 김소라, 김현기, 김혜련, 김효송, 박형순, 이민구, 임선민, 정현철, 조병철
2016Pilot Study of a Next-Generation Sequencing-Based Targeted Anticancer Therapy in Refractory Solid Tumors at a Korean Institution 김상우, 김혜련, 박형순, 이민구
2016Benefit of Adjuvant Chemotherapy After Curative Resection of Lung Metastasis in Colorectal Cancer김대준, 박형순, 범승훈, 신상준, 안중배, 이민구, 이진구, 이창영, 정민규, 허수진
2016Knockdown of RPL9 expression inhibits colorectal carcinoma growth via the inactivation of Id-1/NF-κB signaling axis이민구
2016Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice 이민구
2015Phase II clinical and exploratory biomarker study of dacomitinib in patients with recurrent and/or metastatic squamous cell carcinoma of head and neck고윤우, 권형주, 김주항, 김한상, 김혜련, 백순명, 이민구, 이지현, 정인경, 조병철, 최은창
2015microDuMIP: target-enrichment technique for microarray-based duplex molecular inversion probes 김한상, 이민구, 이지현, 한수민
2015Genetic testing of Korean familial hypercholesterolemia using whole-exome sequencing 박성하, 이민구, 이병권, 이상학, 이지현, 장양수, 한수민
2015Targeted next-generation sequencing for the genetic diagnosis of dysferlinopathy김승민, 신하영, 이민구, 이정환, 이지현, 최영철
2015Proprotein convertase 5/6a is associated with bone morphogenetic protein-2-induced squamous cell differentiation윤주헌, 이민구, 이상남
2015Identification of a novel p.Q1772X ANK1 mutation in a Korean family with hereditary spherocytosis 고홍, 김승, 이민구, 이지현
2015GWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy김원주, 이민구, 이병인, 이지현, 조양제, 허경
2015Regulation of phagocytosis and cytokine secretion by store-operated calcium entry in primary isolated murine microglia김주영, 이민구
2015Non-syndromic hearing loss caused by the dominant cis mutation R75Q with the recessive mutation V37I of the GJB2 (Connexin 26) gene 이경아, 이민구, 정진세, 최재영
2015Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP김연정, 이민구
2015Analysis of conventional and unconventional trafficking of CFTR and other membrane proteins김주영, 이민구, 지헌영
2015The full repertoire of Drosophila gustatory receptors for detecting an aversive compound 김연정, 문석준, 이민구, 정용택
2015Novel COCH p.V123E Mutation, Causative of DFNA9 Sensorineural Hearing Loss and Vestibular Disorder, Shows Impaired Cochlin Post-Translational Cleavage and Secretion김한상, 이민구, 정진세, 최재영
2015A Novel BEST1 Mutation in Autosomal Recessive Bestrophinopathy김응권, 이민구, 이성철, 이승규, 이지환, 전익현, 최승일
2015Selective serotonin reuptake inhibitors facilitate ANO6 (TMEM16F) current activation and phosphatidylserine exposure송재우, 이민구, 전익현, 정진세
2014A newly discovered LGI1 mutation in Korean family with autosomal dominant lateral temporal lobe epilepsy김도의, 김소원, 이문규, 이민구, 이병인, 이지현, 조양제, 허경
2014Na+/H+ Exchanger Regulatory Factor 3 Is Critical for Multidrug Resistance Protein 4-Mediated Drug Efflux in the Kidney박준희, 이민구
2014Shank2 mutant mice display a hypersecretory response to cholera toxin노신혜, 박준희, 이민구, 이정수, 정은석, 정진세, 지헌영
2014Role of calcium signaling in epithelial bicarbonate secretion이민구, 정진세
2014Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis. 박현우, 이민구, 정진세
2014Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers 김대준, 김세규, 김은영, 김주항, 김한상, 김혜련, 배미경, 심효섭, 이민구, 이지현, 이진구, 이창영, 장준, 정경영, 정지예, 조병철
2014Does calmodulin regulate the bicarbonate permeability of ANO1/TMEM16A or not? 이민구, 정진세
2013Dynamic modulation of ANO1/TMEM16A HCO3− permeability by Ca2+/calmodulin 윤주헌, 이민구, 정진세
2013Association of genetic variation in chitotriosidase with atopy in Korean children김경원, 김규언, 김미나, 박준희, 손명현, 이경은, 이민구, 이지현, 이희선, 허원일, 홍정연
2013WNK4 inhibits plasma membrane targeting of NCC through regulation of syntaxin13 SNARE formation김주영, 박현우, 이민구, 정우영
2013Combined effects of an antioxidant and caspase inhibitor on the reversal of hepatic fibrosis in rats김도영, 노원상, 박영년, 이관식, 이민구, 이정일, 정숙인, 한광협
2013Genetic Variations of ABCC2 Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients 김원주, 이민구, 이지현, 조양제
2013Proximal Dominant Hereditary Motor and Sensory Neuropathy With Proximal Dominance Association With Mutation in the TRK-Fused Gene박형순, 이민구, 이지현
2013Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin이민구
2012Opposite regulatory effects of TRPC1 and TRPC5 on neurite outgrowth in PC12 cells.김주영, 박현우, 이민구, 정우영
2012Regulation of SLC26A3 activity by NHERF4 PDZ-mediated interaction.김주영, 박준희, 이민구, 이지현
2012Transepithelial Bicarbonate Secretion: Lessons from the Pancreas. 박현우, 이민구
2012The relation of serotonin-related gene and COMT gene polymorphisms with criminal behavior in schizophrenic disorder고경봉, 김소원, 이민구, 이영준, 최은희, 한무영
2012Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function이민구, 이정수, 정은석, 지헌영
2012Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion 박현우, 이민구
2012Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins 이민구, 지헌영
2012Non-classical membrane trafficking processes galore이민구
2012Rescue of epithelial HCO3- secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del 이민구
2011Rifampin enhances the glucose-lowering effect of metformin and increases OCT1 mRNA levels in healthy participants박경수, 박민수, 이동환, 이민구, 임아영, 정재용, 조성권
2011반복적인 가래 기침을 주소로 내원한 9세 여아에서 발견된 낭성섬유증 1례: CFTR 유전자 변이 D339Y, Q220X 김경원, 김규언, 김명준, 손명현, 이민구
2011WNK4 kinase negatively regulates the surface expression of muscarinic M3 receptor.김경환, 김주영, 박현우, 이민구, 정우영
2011Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature 김경환, 김주영, 박현우, 이민구, 이영호, 최수경
2011Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway.김경환, 이민구
2011A synonymous variation in protease-activated receptor-2 is associated with atopy in Korean children김경원, 김경환, 김규언, 김미나, 김소원, 손명현, 이민구, 이지현, 지헌영
2011A small molecule that binds to an ATPase domain of Hsc70 promotes membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator.이민구, 지헌영
2011사람중이점막세포에서 Uridine-5’-Triphosphate 자극에 의한 Cystic Fibrosis Transmembrane Conductance Regulator와 Ca2+-Activated Chloride Channel을 통한 Chloride 분비 활성화 손은진, 이민구, 이원상, 지헌영, 최재영
2011Association of a synonymous GAT3 polymorphism with antiepileptic drug pharmacoresistance김원주, 이민구
2011The cystic fibrosis transmembrane conductance regulator's expanding SNARE interactome이민구, 지헌영
2011The effect of the newly developed angiotensin receptor II antagonist fimasartan on the pharmacokinetics of atorvastatin in relation to OATP1B1 in healthy male volunteers이민구
2011Lack of association between response of OROS-methylphenidate and norepinephrine transporter (SLC6A2) polymorphism in Korean ADHD김소원, 이민구, 이성희
2010Effects of SLCO1B1 and ABCB1 genotypes on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Korean subjects이민구, 이윤정, 임아영, 장성복, 정재용
2010The L441P mutation of cystic fibrosis transmembrane conductance regulator and its molecular pathogenic mechanisms in a Korean patient with cystic fibrosis 김경환, 김소원, 김정호, 이민구, 이지현, 지헌영
2010Selective inhibition of MDR1 (ABCB1) by HM30181 increases oral bioavailability and therapeutic efficacy of paclitaxel.곽진오, 김경환, 김소원, 이민구, 이성희, 이지현
2010A nonsynonymous variation in MRP2/ABCC2 is associated with neurological adverse drug reactions of carbamazepine in patients with epilepsy.김경환, 김소원, 김원주, 이민구, 이병인, 이성희, 이지현, 조양제, 허경
2010BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction 김경환, 김주영, 박현우, 이민구, 이정수
2010MRP1 polymorphisms associated with citalopram response in patients with major depression김세주, 김소원, 이민구, 이성희, 이재면, 이지현
2010Dynamic regulation of CFTR bicarbonate permeability by [Cl-]i and its role in pancreatic bicarbonate secretion.김경식, 김경환, 김주영, 남주현, 박현우, 윤재석, 이민구, 이정수
2010Association of ABCB1 polymorphisms with the efficacy of ondansetron for postoperative nausea and vomiting.이민구, 이성희, 최승호, 최은경
2010Association between cystic fibrosis transmembrane conductance regulator gene mutations and susceptibility for childhood asthma in Korea 김경원, 김경환, 김규언, 손명현, 이민구, 이지현
2010Syntaxin 16 binds to cystic fibrosis transmembrane conductance regulator and regulates its membrane trafficking in epithelial cells. 김경환, 이민구, 지헌영
2009Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.김경원, 김경환, 김규언, 김소원, 손명현, 이민구, 이성희, 이지현
2009Synaptic scaffolding molecule binds to and regulates vasoactive intestinal polypeptide type-1 receptor in epithelial cells.김경식, 김경환, 김주영, 김호근, 박현우, 이민구, 지헌영
2009The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth 김경환, 김주영, 이민구
2009Chloride intracellular channel 1 regulates osteoblast differentiation이민구
2009Effects of KR-33028, a novel Na+/H+ exchanger-1 inhibitor, on glutamate-induced neuronal cell death and ischemia-induced cerebral infarct윤재석, 이민구
2009Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1 이민구, 이정호
2009PDZ-based adaptor proteins in epithelial anion transport and VIP receptor regulation 김경환, 박현우, 이민구, 지헌영
2008Physical interactions and functional coupling between Daxx and sodium hydrogen exchanger 1 in ischemic cell death 김은희, 김준오, 김혜영, 이민구
2008Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans.김경환, 박경수, 이민구
2008기니 픽의 수술 후 장 폐색 모델에서 위장관 운동에 대한 Itopride Hydrochloride의 효과 박효진, 이민구, 이영호
2008Pancreatitis: the neglected duct이민구
2008PAR2 exerts local protection against acute pancreatitis via modulation of MAP kinase and MAP kinase phosphatase signaling. 김경환, 윤재석, 이민구
2008한국인 낭성 섬유증 진단을 위한 표준화된 땀 유발 염소 농도 분석 김정호, 이민구
2008Heterogeneity in the processing defect of SLC26A4 mutants.김경환, 윤재석, 이민구, 이원상
2007Molecular and functional expression of anion exchangers in cultured normal human nasal epithelial cells손은진, 윤주헌, 이민구, 최재영
2007Effect of Slc26a6 deletion on apical Cl−/HCO3− exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct 이민구
2007TRPC channels as STIM1-regulated store-operated channels김주영, 이민구
2007Pharmacodynamic characteristics and cardioprotective effects of new NHE1 inhibitors김경환, 이민구
2007Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors 김경환, 이민구, 이지현
2007Interleukin-1β upregulates Na+-K+-2Cl− cotransporter in human middle ear epithelia손은진, 윤주헌, 이민구, 최재영
2007MRP2 haplotypes confer differential susceptibility to toxic liver injury김경환, 안상훈, 이민구, 이정호, 이지현, 전재윤, 최지하, 한광협
2006Shank2 Associates with and Regulates Na+/H+ Exchanger 3 김경환, 이민구
2005Expression of Na+/H+ exchanger isoforms in normal human nasal epithelial cells and functional activity of Na+/H+ exchanger 1 in intracellular pH regulation김창훈, 신지현, 유종범, 윤주헌, 이민구, 이정권, 최재영
2005Gene SNPs and mutations in clinical genetic testing: Haplotype-based testing and analysis이민구, 이지현, 최지하
2005Base Treatment Corrects Defects Due to Misfolding of Mutant Cystic Fibrosis Transmembrane Conductance Regulator김경환, 이민구
2004Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis김인숙, 김주희, 김철훈, 안영수, 이민구, 정광철, 최준정
2004Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis김경환, 이민구, 조경희
2004Purinergic Stimulation Induces Ca2+-dependent Activation of Na+-K+-2Cl- Cotransporter in Human Nasal Epithelia 윤주헌, 이민구, 최재영
2004Inhibitory regulation of cystic fibrosis transmembrane conductance regulator anion-transporting activities by Shank2 김경환, 김주영, 이민구, 이지현
2004Membrane-specific expression of functional purinergic receptors in normal human nasal epithelial cells 김성식, 김진영, 김창훈, 신지현, 윤주헌, 이민구, 이정권, 최재영
2003Multiple Effects of SERCA2b Mutations Associated with Darier's Disease 김경환, 이민구
2003Pancreatitis from bile reflux-again? - Reply김경환, 김주영, 신동민, 이민구
2003Ca2+ Activates Cystic Fibrosis Transmembrane Conductance Regulator- and Cl−-dependent HCOFormula Transport in Pancreatic Duct Cells 김경환, 안덕선, 안우인, 이민구, 이진아
2003A haplotype-based molecular analysis of CFTR mutations associated with respiratory and pancreatic diseases 김경환, 김동수, 박승우, 송시영, 윤주헌, 이민구, 이지현, 장준, 최지하
2002A protein sequence that can encode native structure by disfavoring alternate conformations이민구
2002A molecular mechanism for aberrant CFTR-dependent HCO3- transport in cystic fibrosis 김경환, 김주영, 이민구
2002Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells김경환, 김주영, 신동민, 이민구
2002The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3 김주영, 이민구
2001Regulatory interaction between the cystic fibrosis transmembrane conductance regulator and HCO3- salvage mechanisms in model systems and the mouse pancreatic duct 김경환, 김주영, 이민구
2001Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosis 이민구
2001HCOFormula Salvage Mechanisms in the Submandibular Gland Acinar and Duct Cells 이민구
2001Intracellular calcium mobilization induces immediate early gene pip92 via Src and mitogen-activated protein kinase in immortalized hippocampal cells 안영수, 안우인, 이민구

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