2024 | Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression | NATURE CANCER |
2024 | Specific kinesin and dynein molecules participate in the unconventional protein secretion of transmembrane proteins
| KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY |
2024 | Genome-wide association analysis reveals the associations of NPHP4, TYW1-AUTS2 and SEMA6D for Behçet's disease and HLA-B*46:01 for its intestinal involvement | DIGESTIVE AND LIVER DISEASE |
2024 | Multi-locus pathogenic variation identified in a patient with craniosynostosis | AMERICAN JOURNAL OF MEDICAL GENETICS PART A |
2023 | Novel small molecule-mediated restoration of the surface expression and anion exchange activity of mutated pendrin causing Pendred syndrome and DFNB4
| BIOMEDICINE & PHARMACOTHERAPY |
2023 | LRRC6 regulates biogenesis of motile cilia by aiding FOXJ1 translocation into the nucleus
| CELL COMMUNICATION AND SIGNALING |
2022 | Multicenter Surveillance of Cystic Fibrosis in Korean Children
| ALLERGY ASTHMA & IMMUNOLOGY RESEARCH |
2022 | TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike
| ADVANCED SCIENCE |
2022 | Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition
| CELL REPORTS |
2022 | Autophagy-Related Pathways in Vesicular Unconventional Protein Secretion
| FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY |
2022 | Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation
| HUMAN GENETICS |
2021 | Secretory autophagy machinery and vesicular trafficking are involved in HMGB1 secretion
| AUTOPHAGY |
2021 | Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing | TRANSPLANTATION |
2021 | Molecular Characterization of Biliary Tract Cancer Predicts Chemotherapy and Programmed Death 1/Programmed Death-Ligand 1 Blockade Responses | HEPATOLOGY |
2021 | Regeneration of infarcted mouse hearts by cardiovascular tissue formed via the direct reprogramming of mouse fibroblasts | NATURE BIOMEDICAL ENGINEERING |
2021 | A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators | PHARMACOGENETICS AND GENOMICS |
2021 | Plasma Membrane Localized GCaMP-MS4A12 by Orai1 Co-Expression Shows Thapsigargin- and Ca 2+-Dependent Fluorescence Increases
| MOLECULES AND CELLS |
2020 | Isoproterenol-induced hypertrophy of neonatal cardiac myocytes and H9c2 cell is dependent on TRPC3-regulated Ca V 1.2 expression | CELL CALCIUM |
2020 | Molecular Diagnosis of Craniosynostosis Using Targeted Next-Generation Sequencing | NEUROSURGERY |
2020 | Bicarbonate permeation through anion channels: its role in health and disease | PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY |
2020 | Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus
| CELL REPORTS |
2020 | ADCK4 Deficiency Destabilizes the Coenzyme Q Complex, Which Is Rescued by 2,4-Dihydroxybenzoic Acid Treatment | JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY |
2020 | DNAJC14 Ameliorates Inner Ear Degeneration in the DFNB4 Mouse Model
| MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT |
2020 | Grasp55 -/- Mice Display Impaired Fat Absorption and Resistance to High-Fat Diet-Induced Obesity
| NATURE COMMUNICATIONS |
2020 | Digenic Inheritance of Mutations in EPHA2 and SLC26A4 in Pendred Syndrome
| NATURE COMMUNICATIONS |
2020 | IRE1α Kinase-Mediated Unconventional Protein Secretion Rescues Misfolded CFTR and Pendrin
| SCIENCE ADVANCES |
2020 | Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related Disorders
| CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY |
2019 | Functional Characterization of Pharmcogenetic Variants of Human Cytochrome P450 2C9 in Korean Populations
| BIOMOLECULES & THERAPEUTICS |
2019 | Rare KCNQ4 variants found in public databases underlie impaired channel activity that may contribute to hearing impairment | Experimental and Molecular Medicine |
2019 | Systematic evaluation of gene variants linked to hearing loss based on allele frequency threshold and filtering allele frequency
| Scientific Reports |
2019 | Temperature-dependent increase in the calcium sensitivity and acceleration of activation of ANO6 chloride channel variants
| Scientific Reports |
2019 | A recurrent mutation in KCNQ4 in Korean families with nonsyndromic hearing loss and rescue of the channel activity by KCNQ activators | HUMAN MUTATION |
2018 | NPP1 is responsible for potent extracellular ATP hydrolysis as NTPDase1 in primary cultured murine microglia
| PURINERGIC SIGNALLING |
2018 | Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2. | MOLECULAR AND CELLULAR BIOCHEMISTRY |
2018 | Specific autophagy and ESCRT components participate in the unconventional secretion of CFTR | AUTOPHAGY |
2018 | Unconventional secretion of transmembrane proteins | SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY |
2018 | Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth
| GENOME RESEARCH |
2018 | Unconventional protein secretion - new insights into the pathogenesis and therapeutic targets of human diseases | JOURNAL OF CELL SCIENCE |
2018 | ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms
| PLOS GENETICS |
2018 | Neopepsee: accurate genome-level prediction of neoantigens by harnessing sequence and amino acid immunogenicity information | ANNALS OF ONCOLOGY |
2018 | Survival of Cancer Stem-Like Cells Under Metabolic Stress via CaMK2α-mediated Upregulation of Sarco/Endoplasmic Reticulum Calcium ATPase Expression | CLINICAL CANCER RESEARCH |
2017 | Hippocampus-Dependent Goal Localization by Head-Fixed Mice in Virtual Reality
| ENEURO |
2017 | ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer | BRITISH JOURNAL OF CANCER |
2017 | Chronological Change of Right Ventricle by Chronic Intermittent Hypoxia in Mice | SLEEP |
2017 | A coding variant in FTO confers susceptibility to thiopurine-induced leukopenia in East Asian patients with IBD | GUT |
2017 | Adult-Onset Vitelliform Macular Dystrophy caused by BEST1 p.Ile38Ser Mutation is a Mild Form of Best Vitelliform Macular Dystrophy
| SCIENTIFIC REPORTS |
2017 | Comparison of clinical outcomes between wavefront-optimized versus corneal wavefront-guided transepithelial photorefractive keratectomy for myopic astigmatism | JOURNAL OF CATARACT AND REFRACTIVE SURGERY |
2017 | UDP-Induced Phagocytosis and ATP-Stimulated Chemotactic Migration Are Impaired in STIM1-/- Microglia In Vitro and In Vivo
| MEDIATORS OF INFLAMMATION |
2017 | Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice | NEUROPHARMACOLOGY |
2017 | Targeted Next-Generation Sequencing for Comprehensive Genetic Profiling of Pharmacogenes | CLINICAL PHARMACOLOGY & THERAPEUTICS |