| 2022 | Enhanced tumor targeting and timely viral release of mesenchymal stem cells/oncolytic virus complex due to GRP78 and inducible E1B55K expressions greatly increase the antitumor effect of systemic treatment
| MOLECULAR THERAPY-ONCOLYTICS |
| 2021 | Enhanced oncolytic adenoviral production by downregulation of death-domain associated protein and overexpression of precursor terminal protein
| SCIENTIFIC REPORTS |
| 2019 | High levels of Daxx due to low cellular levels of HSP25 in murine cancer cells result in inefficient adenovirus replication
| EXPERIMENTAL AND MOLECULAR MEDICINE |
| 2018 | TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade
| EXPERIMENTAL AND MOLECULAR MEDICINE |
| 2018 | Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth
| GENOME RESEARCH |
| 2017 | Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib.
| YONSEI MEDICAL JOURNAL |
| 2017 | Prime-boost immunization by both DNA vaccine and oncolytic adenovirus expressing GM-CSF and shRNA of TGF-β2 induces anti-tumor immune activation
| ONCOTARGET |
| 2016 | Survivin silencing and TRAIL expression using oncolytic adenovirus increase anti-tumorigenic activity in gemcitabine-resistant pancreatic cancer cells | APOPTOSIS |
| 2015 | Silencing Daxx increases the anti-tumor activity of a TRAIL/shRNA Bcl-xL-expressing oncolytic adenovirus through enhanced viral replication and cellular arrest | CELLULAR SIGNALLING |
| 2015 | Ratio of phosphorylated HSP27 to nonphosphorylated HSP27 biphasically acts as a determinant of cellular fate in gemcitabine-resistant pancreatic cancer cells | CELLULAR SIGNALLING |
| 2014 | Establishment of a mouse melanoma model system for the efficient infection and replication of human adenovirus type 5-based oncolytic virus | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2013 | Crosstalk from survival to necrotic death coexists in DU-145 cells by curcumin treatment: Inhibition of apoptosis by caspase degradation. | CELLULAR SIGNALLING |
| 2013 | The effectiveness of the oncolytic activity induced by Ad5/F35 adenoviral vector is dependent on the cumulative cellular conditions of survival and autophagy | INTERNATIONAL JOURNAL OF ONCOLOGY |
| 2013 | c-Cbl shRNA-expressing adenovirus sensitizes TRAIL-induced apoptosis in prostate cancer DU-145 through increases of DR4/5 | CANCER GENE THERAPY |
| 2013 | Transforming growth factor-β gene silencing using adenovirus expressing TGF-β1 or TGF-β2 shRNA | CANCER GENE THERAPY |
| 2013 | TRAIL/MEKK4/p38/HSP27/Akt survival network is biphasically modulated by the Src/CIN85/c-Cbl complex | CELLULAR SIGNALLING |
| 2012 | HSP27 modulates survival signaling networks in cells treated with curcumin and TRAIL | CELLULAR SIGNALLING |
| 2011 | MEKK1/MEKK4 are responsible for TRAIL-induced JNK/p38 phosphorylation
| ONCOLOGY REPORTS |
| 2011 | TRAIL-induced caspase/p38 activation is responsible for the increased catalytic and invasive activities of Akt
| INTERNATIONAL JOURNAL OF ONCOLOGY |
| 2010 | c-Cbl acts as a mediator of Src-induced activation of the PI3K-Akt signal transduction pathway during TRAIL treatment.
| CELLULAR SIGNALLING |
| 2010 | c-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance
| CELLULAR SIGNALLING |
| 2008 | Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily
| CELLULAR SIGNALLING |
| 2007 | Evidence for two modes of development of acquired tumor necrosis factor-related apoptosis-inducing ligand resistance - Involvement of Bcl-xL
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2007 | Differential activation of the JNK signal pathway by UV irradiation and glucose deprivation | CELLULAR SIGNALLING |
| 2005 | Pretreatment of Acetylsalicylic Acid Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand-induced Apoptosis by Down-regulating BCL-2 Gene Expression
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2005 | Cross-talk between JIP3 and JIP1 during Glucose Deprivation: SEK1-JNK2 and Akt1 act as mediators
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2005 | Dissociation of Akt1 from its negative regulator JIP1 is mediated through the ASK1–MEK–JNK signal transduction pathway during metabolic oxidative stress: A negative feedback loop
| JOURNAL OF CELL BIOLOGY |
| 2005 | Signal Pathway of Hypoxia-Inducible Factor-1α Phosphorylation and its Interaction with von Hippel-Lindau Tumor Suppressor Protein During Ischemia in MiaPaCa-2 Pancreatic Cancer Cells
| CLINICAL CANCER RESEARCH |
| 2004 | Tryptophan 621 and serine 667 residues of Daxx regulate its nuclear export during glucose deprivation
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2004 | Low extracellular pH augments TRAIL-induced apoptotic death through the mitochondria-mediated caspase signal transduction pathway | EXPERIMENTAL CELL RESEARCH |
| 2004 | Daxx deletion mutant (amino acids 501-625)-induced apoptosis occurs through the JNK/p38-Bax-dependent mitochondrial pathway | JOURNAL OF CELLULAR BIOCHEMISTRY |
| 2003 | Role of the ASK1-SEK1-JNK1-HIPK1 Signal in Daxx Trafficking and ASK1 Oligomerization
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2003 | Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: Hydrogen peroxide as a major second messenger of metabolic oxidative stress | JOURNAL OF CELLULAR BIOCHEMISTRY |
| 2003 | Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1
| BIOCHEMICAL JOURNAL |
| 2003 | Reconstitution of galectin-3 alters glutathione content and potentiates TRAIL-induced cytotoxicity by dephosphorylation of Akt | EXPERIMENTAL CELL RESEARCH |
| 2003 | Effect of glucose concentration on activation of the ASK1–SEK1–JNK1 signal transduction pathway | JOURNAL OF CELLULAR BIOCHEMISTRY |
| 2003 | dl-VSVG-LacZ, a VSV-G epitope incorporated adenoviurs exhibit marked enhancement in gene transduction efficiency | HUMAN GENE THERAPY |
| 2003 | Optimization of vesicular stomatitis virus-G pseudotyped feline immunodeficiency virus vector for minimized cytotoxicity with efficient gene transfer | VIRUS RESEARCH |
| 2002 | Role of glutaredoxin in metabolic oxidative stress - Glutaredoxin as a sensor of oxidative stress mediated by H2O2 | JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2002 | Enhancement of metabolic oxidative stress-induced cytotoxicity by the thioredoxin inhibitor 1-methylpropyl 2-imidazolyl disulfide is mediated through the ASK1-SEK1-JNK1 pathway
| MOLECULAR PHARMACOLOGY |
| 2001 | Efficient gene transfer of VSV-G pseudotyped retroviral vector to human brain tumor
| GENE THERAPY |
| 2000 | Transduction effect of antisense K-ras on malignant phenotypes in gastric cancer cells | Cancer Letters |
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