2022 | Magnetogenetics with Piezo1 Mechanosensitive Ion Channel for CRISPR Gene Editing | NANO LETTERS |
2022 | High-throughput functional evaluation of human cancer-associated mutations using base editors | NATURE BIOTECHNOLOGY |
2022 | Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair
| STEM CELL RESEARCH |
2022 | Basic Principles and Clinical Applications of CRISPR-Based Genome Editing
| YONSEI MEDICAL JOURNAL |
2022 | In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model
| THERANOSTICS |
2022 | Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases | NATURE BIOMEDICAL ENGINEERING |
2021 | Improving CRISPR tools by elucidating DNA repair | NATURE BIOTECHNOLOGY |
2021 | Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain
| NATURE COMMUNICATIONS |
2021 | Recording of elapsed time and temporal information about biological events using Cas9 | CELL |
2021 | Predicting the efficiency of prime editing guide RNAs in human cells | NATURE BIOTECHNOLOGY |
2020 | Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer | CELL DEATH AND DIFFERENTIATION |
2020 | Prediction of the sequence-specific cleavage activity of Cas9 variants | NATURE BIOTECHNOLOGY |
2020 | Sequence-specific prediction of the efficiencies of adenine and cytosine base editors | NATURE BIOTECHNOLOGY |
2020 | Chemical Controllable Gene Drive in Drosophila | ACS SYNTHETIC BIOLOGY |
2020 | High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells | NATURE BIOMEDICAL ENGINEERING |
2019 | LIN28A loss of function is associated with Parkinson's disease pathogenesis
| EMBO JOURNAL |
2019 | SpCas9 activity prediction by DeepSpCas9, a deep learning-based model with high generalization performance
| Science Advances |
2019 | Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis
| Molecular Therapy Oncolytics |
2019 | Therapeutic application of the CRISPR system: current issues and new prospects | Human Genetics |
2019 | En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements
| NUCLEIC ACIDS RESEARCH |
2018 | In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
2018 | Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination | NEURON |
2018 | Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption | NUCLEIC ACIDS RESEARCH |
2018 | Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth
| GENOME RESEARCH |
2018 | Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity | NATURE BIOTECHNOLOGY |
2017 | Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction
| STEM CELLS TRANSLATIONAL MEDICINE |
2017 | RanBPM: a potential therapeutic target for modulating diverse physiological disorders | DRUG DISCOVERY TODAY |
2017 | Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division.
| NATURE COMMUNICATIONS |
2017 | Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes | STEM CELLS |
2017 | In vivo high-throughput profiling of CRISPR-Cpf1 activity | NATURE METHODS |
2017 | Cell-Penetrating Peptide-Mediated Delivery of Cas9 Protein and Guide RNA for Genome Editing | Methods in Molecular Biology (Clifton, N.J.) |
2017 | Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia | AMERICAN JOURNAL OF HUMAN GENETICS |
2016 | Heroes of peer review: Hyongbum (Henry) Kim
| GENOME BIOLOGY |
2016 | Elucidation of Relevant Neuroinflammation Mechanisms Using Gene Expression Profiling in Patients with Amyotrophic Lateral Sclerosis
| PLOS ONE |
2016 | Environmental enrichment enhances synaptic plasticity by internalization of striatal dopamine transporters | JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM |
2016 | In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia
| MOLECULAR THERAPY |
2016 | Generation of ΔF508-CFTR T84 cell lines by CRISPR/Cas9-mediated genome editing | BIOTECHNOLOGY LETTERS |
2016 | Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury
| INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES |
2016 | Regulation of pluripotency and differentiation by deubiquitinating enzymes. | CELL DEATH AND DIFFERENTIATION |
2016 | Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice
| SCIENTIFIC REPORTS |
2016 | Designed nucleases for targeted genome editing
| PLANT BIOTECHNOLOGY JOURNAL |
2015 | CRISPR/Cas9 system as an innovative genetic engineering tool: Enhancements in sequence specificity and delivery methods | BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER |
2015 | Effective Gene Delivery into Human Stem Cells with a Cell-Targeting Peptide-Modified Bioreducible Polymer | SMALL |
2015 | Diabetic Mesenchymal Stem Cells Are Ineffective for Improving Limb Ischemia Due to Their Impaired Angiogenic Capability
| CELL TRANSPLANTATION |
2015 | Recent developments and clinical studies utilizing engineered zinc finger nuclease technology | CELLULAR AND MOLECULAR LIFE SCIENCES |
2015 | Rh D blood group conversion using transcription activator-like effector nucleases
| NATURE COMMUNICATIONS |
2014 | Doxycycline enhances survival and self-renewal of human pluripotent stem cells
| STEM CELL REPORTS |
2014 | Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells.
| JOURNAL OF VIROLOGY |