Browsing by Yonsei Author : Kim, Hyongbum

Name:
Kim, Hyongbum [김형범] http://orcid.org/0000-0002-4693-738X
Department :
College of Medicine (의과대학) - Dept. of Pharmacology (약리학교실)
Y-HRN :
(Yonsei Health Research Network)
Scopus ID :
(24280276300)

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Issue DateTitleJournal Title
2020High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cellsNATURE BIOMEDICAL ENGINEERING
2019Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis Molecular Therapy Oncolytics
2019SpCas9 activity prediction by DeepSpCas9, a deep learning-based model with high generalization performance Science Advances
2019Therapeutic application of the CRISPR system: current issues and new prospectsHuman Genetics
2019En bloc and segmental deletions of human XIST reveal X chromosome inactivation-involving RNA elements NUCLEIC ACIDS RESEARCH
2018In vivo gene correction with targeted sequence substitution through microhomology-mediated end joiningBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2018Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth GENOME RESEARCH
2018Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption.NUCLEIC ACIDS RESEARCH
2018Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical DyslaminationNEURON
2018Deep learning improves prediction of CRISPR-Cpf1 guide RNA activityNATURE BIOTECHNOLOGY
2017Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction STEM CELLS TRANSLATIONAL MEDICINE
2017RanBPM: a potential therapeutic target for modulating diverse physiological disordersDRUG DISCOVERY TODAY
2017Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division. NATURE COMMUNICATIONS
2017Concise Review: Fate Determination of Stem Cells by Deubiquitinating EnzymesSTEM CELLS
2017In vivo high-throughput profiling of CRISPR-Cpf1 activityNATURE METHODS
2017Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical DysplasiaAMERICAN JOURNAL OF HUMAN GENETICS
2017Cell-Penetrating Peptide-Mediated Delivery of Cas9 Protein and Guide RNA for Genome EditingMethods in Molecular Biology (Clifton, N.J.)
2016Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
2016Heroes of peer review: Hyongbum (Henry) Kim GENOME BIOLOGY
2016Regulation of pluripotency and differentiation by deubiquitinating enzymes.CELL DEATH AND DIFFERENTIATION
2016Generation of ΔF508-CFTR T84 cell lines by CRISPR/Cas9-mediated genome editingBIOTECHNOLOGY LETTERS
2016Elucidation of Relevant Neuroinflammation Mechanisms Using Gene Expression Profiling in Patients with Amyotrophic Lateral Sclerosis PLOS ONE
2016Environmental enrichment enhances synaptic plasticity by internalization of striatal dopamine transportersJOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
2016In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia MOLECULAR THERAPY
2016Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice SCIENTIFIC REPORTS
2016Designed nucleases for targeted genome editing PLANT BIOTECHNOLOGY JOURNAL
2015Effective Gene Delivery into Human Stem Cells with a Cell-Targeting Peptide-Modified Bioreducible PolymerSMALL
2015Diabetic Mesenchymal Stem Cells Are Ineffective for Improving Limb Ischemia Due to Their Impaired Angiogenic Capability CELL TRANSPLANTATION
2015CRISPR/Cas9 system as an innovative genetic engineering tool: Enhancements in sequence specificity and delivery methodsBIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
2015Rh D blood group conversion using transcription activator-like effector nucleases NATURE COMMUNICATIONS
2015Recent developments and clinical studies utilizing engineered zinc finger nuclease technologyCELLULAR AND MOLECULAR LIFE SCIENCES
2014Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells. JOURNAL OF VIROLOGY
2014Doxycycline enhances survival and self-renewal of human pluripotent stem cells STEM CELL REPORTS
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