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RanBPM: a potential therapeutic target for modulating diverse physiological disorders

Authors
 Soumyadip Das  ;  Bharathi Suresh  ;  Hyongbum (Henry) Kim  ;  Suresh Ramakrishna 
Citation
 DRUG DISCOVERY TODAY, Vol.22(12) : 1816-1824, 2017 
Journal Title
DRUG DISCOVERY TODAY
ISSN
 1359-6446 
Issue Date
2017
Abstract
The Ran-binding protein microtubule-organizing center (RanBPM) is a highly conserved nucleocytoplasmic protein involved in a variety of intracellular signaling pathways that control diverse cellular functions. RanBPM interacts with proteins that are linked to various diseases, including Alzheimer's disease (AD), schizophrenia (SCZ), and cancer. In this article, we define the characteristics of the scaffolding protein RanBPM and focus on its interaction partners in diverse physiological disorders, such as neurological diseases, fertility disorders, and cancer.
Full Text
https://www.sciencedirect.com/science/article/pii/S1359644617300752
DOI
10.1016/j.drudis.2017.08.005
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyongbum(김형범) ORCID logo https://orcid.org/0000-0002-4693-738X
Suresh, Bharathi(호사발레랑가파바라티)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/161476
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