Cited 0 times in

99 5

Functional Nanoplatforms for Enhancement of Chemotherapeutic Index

Authors
 Jaemoon Yang ; Eugene Lee ; Jae-Ho Cheong ; Yong-Min Huh ; Minhee Ku 
Citation
 Anti-Cancer Agents in Medicinal Chemistry, Vol.13(2) : 212~221, 2013 
Journal Title
 Anti-Cancer Agents in Medicinal Chemistry 
ISSN
 1871-5206 
Issue Date
2013
Abstract
Recently, the advancement of nanotechnology has had a significant impact on clinical therapeutics. Advances in biocompatible drug carriers using organic/inorganic nanoparticles have enabled safer and more efficient delivery of anti-cancer agents. In particular, nanoparticles designed and fabricated by sophisticated processes can (as drug carriers) deliver precise doses of multiple anti-cancer agents to target cancer cells, improving therapeutic efficacy and minimizing side effects. In addition, a comprehensive understanding of cancer biology, chemo-resistance, cancer relapse, and metastasis is essential for successful development of combination therapy using nanoparticles. In this review, we discuss the species of functional nanoparticles for delivery of anti-cancer agents and their potential to improve chemotherapeutic indices via combination therapy. We also discuss novel therapeutic strategies using functional nanoparticles developed through multidisciplinary collaboration for combination chemotherapy.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/86981
DOI
10.2174/1871520611313020005
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Surgery
1. 연구논문 > 1. College of Medicine > Yonsei Biomedical Research Center
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
1. 연구논문 > 5. Research Institutes > Yonsei Integrative Research Institute for Cerebral & Cardiovascular Disease
Yonsei Authors
사서에게 알리기
  feedback
Link
 http://www.eurekaselect.com/106438/article
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse