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Association between CHADS2, CHA2DS2-VASc, ATRIA, and Essen Stroke Risk Scores and Functional Outcomes in Acute Ischemic Stroke Patients Who Received Endovascular Thrombectomy

Authors
 Hyung Jun Kim  ;  Moo-Seok Park  ;  Joonsang Yoo  ;  Young Dae Kim  ;  Hyungjong Park  ;  Byung Moon Kim  ;  Oh Young Bang  ;  Hyeon Chang Kim  ;  Euna Han  ;  Dong Joon Kim  ;  JoonNyung Heo  ;  Jin Kyo Choi  ;  Kyung-Yul Lee  ;  Hye Sun Lee  ;  Dong Hoon Shin  ;  Hye-Yeon Choi  ;  Sung-Il Sohn  ;  Jeong-Ho Hong  ;  Jong Yun Lee  ;  Jang-Hyun Baek  ;  Gyu Sik Kim  ;  Woo-Keun Seo  ;  Jong-Won Chung  ;  Seo Hyun Kim  ;  Sang Won Han  ;  Joong Hyun Park  ;  Jinkwon Kim  ;  Yo Han Jung  ;  Han-Jin Cho  ;  Seong Hwan Ahn  ;  Sung Ik Lee  ;  Kwon-Duk Seo  ;  Yoonkyung Chang  ;  Hyo Suk Nam  ;  Tae-Jin Song 
Citation
 JOURNAL OF CLINICAL MEDICINE, Vol.11(19) : 5599, 2022-09 
Journal Title
JOURNAL OF CLINICAL MEDICINE
Issue Date
2022-09
Keywords
endovascular thrombectomy ; functional outcome ; ischemic stroke ; stroke risk score
Abstract
Background: CHADS2, CHA2DS2-VASc, ATRIA, and Essen stroke risk scores are used to estimate thromboembolism risk. We aimed to investigate the association between unfavorable outcomes and stroke risk scores in patients who received endovascular thrombectomy (EVT).

Methods: This study was performed using data from a nationwide, multicenter registry to explore the selection criteria for patients who would benefit from reperfusion therapies. We calculated pre-admission CHADS2, CHA2DS2-VASc, ATRIA, and Essen scores for each patient who received EVT and compared the relationship between these scores and 3-month modified Rankin Scale (mRS) records.

Results: Among the 404 patients who received EVT, 213 (52.7%) patients had unfavorable outcomes (mRS 3-6). All scores were significantly higher in patients with unfavorable outcomes than in those with favorable outcomes. Multivariable logistic regression analysis indicated that CHADS2 and the ATRIA score were positively correlated with unfavorable outcomes after adjusting for body mass index and variables with p < 0.1 in the univariable analysis (CHADS2 score: odds ratio [OR], 1.484; 95% confidence interval [CI], 1.290-1.950; p = 0.005, ATRIA score, OR, 1.128; 95% CI, 1.041-1.223; p = 0.004).

Conclusions: The CHADS2 and ATRIA scores were positively correlated with unfavorable outcomes and could be used to predict unfavorable outcomes in patients who receive EVT.
Files in This Item:
T202204849.pdf Download
DOI
10.3390/jcm11195599
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Kim, Dong Joon(김동준) ORCID logo https://orcid.org/0000-0002-7035-087X
Kim, Byung Moon(김병문) ORCID logo https://orcid.org/0000-0001-8593-6841
Kim, Young Dae(김영대) ORCID logo https://orcid.org/0000-0001-5750-2616
Kim, Jinkwon(김진권) ORCID logo https://orcid.org/0000-0003-0156-9736
Kim, Hyeon Chang(김현창) ORCID logo https://orcid.org/0000-0001-7867-1240
Nam, Hyo Suk(남효석) ORCID logo https://orcid.org/0000-0002-4415-3995
Yoo, Joon Sang(유준상) ORCID logo https://orcid.org/0000-0003-1169-6798
Lee, Kyung Yul(이경열) ORCID logo https://orcid.org/0000-0001-5585-7739
Lee, Hye Sun(이혜선) ORCID logo https://orcid.org/0000-0001-6328-6948
Jung, Yo Han(정요한) ORCID logo https://orcid.org/0000-0002-3048-4718
Heo, JoonNyung(허준녕)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/192054
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