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Alignment of CT images of skull dysmorphology using anatomy-based perpendicular axes

 Sun K Yoo  ;  Yong O Kim  ;  Hee-Joung Kim  ;  Nam H Kim  ;  Young Beom Jang  ;  Kee-Deog Kim  ;  Hye-Yeon Lee 
 Physics in Medicine and Biology, Vol.48(16) : 2681-2695, 2003 
Journal Title
 Physics in Medicine and Biology 
Issue Date
Rigid body registration of 3D CT scans, based on manual identification of homologous landmarks, is useful for the visual analysis of skull dysmorphology. In this paper, a robust and simple alignment method was proposed to allow for the comparison of skull morphologies, within and between individuals with craniofacial anomalies, based on 3D CT scans, and the minimum number of anatomical landmarks, under rigidity and uniqueness constraints. Three perpendicular axes, extracted from anatomical landmarks, define the absolute coordinate system, through a rigid body transformation, to align multiple CT images for different patients and acquisition times. The accuracy of the alignment method depends on the accuracy of the localized landmarks and target points. The numerical simulation generalizes the accuracy requirements of the alignment method. Experiments using a human dried skull specimen, and ten sets of skull CT images (the pre- and post-operative CT scans of four plagiocephaly, and one fibrous dysplasia patients), demonstrated the feasibility of the technique in clinical practice.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anatomy (해부학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Advanced General Dentistry (통합치의학과) > 1. Journal Papers
Yonsei Authors
Kim, Kee Deog(김기덕) ORCID logo https://orcid.org/0000-0003-3055-5130
Kim, Nam Hyun(김남현)
Kim, Hee Joung(김희중)
Yoo, Sun Kook(유선국) ORCID logo https://orcid.org/0000-0002-6032-4686
Lee, Hye Yeon(이혜연) ORCID logo https://orcid.org/0000-0001-6945-1967
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