0 151

Cited 0 times in

Three-Dimensionally Printed Breast Reconstruction Devices Facilitate Nanostructure Surface-Guided Healthy Lipogenesis

Authors
 Wooyeol Baek  ;  Min Sup Kim  ;  Dan Bi Park  ;  Oh Young Joo  ;  Won Jai Lee  ;  Tai Suk Roh  ;  Hak-Joon Sung 
Citation
 ACS BIOMATERIALS SCIENCE & ENGINEERING, Vol.5(10) : 4962-4969, 2019 
Journal Title
 ACS BIOMATERIALS SCIENCE & ENGINEERING 
Issue Date
2019
Keywords
breast reconstruction surgery ; autologous fat carrier ; 3D printing ; poly(caprolactone) ; lipogenesis
Abstract
Significant fat loss is common in silicon implantation with autologous lipofilling, the most popular type of breast surgery. To overcome this, a 3D-printed fat carrier with well-defined 200 μm radial string and spoke structure was developed, followed by an electrospun nanofiber coating on the entire device surface to promote fat adhesion. This device enhanced the mechanical properties comparably to commercial acellular dermal matrix for in vitro adipogenic differentiation of adipose-derived stem cells, implantation compatibility without foreign body responses, and maintenance of healthy lipid droplet structures. These results show the promising potential of this device to facilitate surface-guided lipogenesis in composite breast reconstruction surgery.
Full Text
https://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00985
DOI
10.1021/acsbiomaterials.9b00985
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
Yonsei Authors
Roh, Tai Suk(노태석) ORCID logo https://orcid.org/0000-0001-8681-159X
Baek, Wooyeol(백우열) ORCID logo https://orcid.org/0000-0002-6638-4110
Sung, Hak-Joon(성학준) ORCID logo https://orcid.org/0000-0003-2312-2484
Lee, Won Jai(이원재) ORCID logo https://orcid.org/0000-0003-3056-0503
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/173103
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links