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Three-Dimensionally Printed Breast Reconstruction Devices Facilitate Nanostructure Surface-Guided Healthy Lipogenesis

DC Field Value Language
dc.contributor.author노태석-
dc.contributor.author백우열-
dc.contributor.author성학준-
dc.contributor.author이원재-
dc.date.accessioned2019-12-18T00:33:14Z-
dc.date.available2019-12-18T00:33:14Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/173103-
dc.description.abstractSignificant fat loss is common in silicon implantation with autologous lipofilling, the most popular type of breast surgery. To overcome this, a 3D-printed fat carrier with well-defined 200 μm radial string and spoke structure was developed, followed by an electrospun nanofiber coating on the entire device surface to promote fat adhesion. This device enhanced the mechanical properties comparably to commercial acellular dermal matrix for in vitro adipogenic differentiation of adipose-derived stem cells, implantation compatibility without foreign body responses, and maintenance of healthy lipid droplet structures. These results show the promising potential of this device to facilitate surface-guided lipogenesis in composite breast reconstruction surgery.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherAmerican Chemical Society-
dc.relation.isPartOfACS BIOMATERIALS SCIENCE & ENGINEERING-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleThree-Dimensionally Printed Breast Reconstruction Devices Facilitate Nanostructure Surface-Guided Healthy Lipogenesis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Plastic and Reconstructive Surgery (성형외과학교실)-
dc.contributor.googleauthorWooyeol Baek-
dc.contributor.googleauthorMin Sup Kim-
dc.contributor.googleauthorDan Bi Park-
dc.contributor.googleauthorOh Young Joo-
dc.contributor.googleauthorWon Jai Lee-
dc.contributor.googleauthorTai Suk Roh-
dc.contributor.googleauthorHak-Joon Sung-
dc.identifier.doi10.1021/acsbiomaterials.9b00985-
dc.contributor.localIdA01297-
dc.contributor.localIdA04949-
dc.contributor.localIdA01958-
dc.contributor.localIdA03005-
dc.relation.journalcodeJ03391-
dc.identifier.eissn2373-9878-
dc.identifier.urlhttps://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.9b00985-
dc.subject.keywordbreast reconstruction surgery-
dc.subject.keywordautologous fat carrier-
dc.subject.keyword3D printing-
dc.subject.keywordpoly(caprolactone)-
dc.subject.keywordlipogenesis-
dc.contributor.alternativeNameRoh, Tai Suk-
dc.contributor.affiliatedAuthor노태석-
dc.contributor.affiliatedAuthor백우열-
dc.contributor.affiliatedAuthor성학준-
dc.contributor.affiliatedAuthor이원재-
dc.citation.volume5-
dc.citation.number10-
dc.citation.startPage4962-
dc.citation.endPage4969-
dc.identifier.bibliographicCitationACS BIOMATERIALS SCIENCE & ENGINEERING, Vol.5(10) : 4962-4969, 2019-
dc.identifier.rimsid63757-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers

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