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Biological efficacy of two mineral trioxide aggregate (MTA)-based materials in a canine model of pulpotomy

 Myeongyeon LEE  ;  Chung-Min KANG  ;  Je Seon SONG  ;  Yooseok SHIN  ;  Seunghye KIM  ;  Seong-Oh KIM  ;  Hyung-Jun CHOI 
 Dental Materials Journal, Vol.36(1) : 41-47, 2017 
Journal Title
 Dental Materials Journal 
Issue Date
Aluminum Compounds* ; Animals ; Calcium Compounds* ; Dental Pulp ; Dogs ; Drug Combinations ; Odontoblasts ; Oxides* ; Pulpotomy* ; Root Canal Filling Materials ; Silicates* ; Tooth
Endocem Zr ; Mineral trioxide aggregate ; ProRoot MTA ; Pulpotomy
The aim of this study was to compare the biocompatibility of Endocem Zr® and ProRoot MTA® by histopathologic analysis in a canine model of pulpotomy. This study utilized 39 teeth of two beagle dogs. The exposed pulp tissues were treated by pulpotomy using ProRoot MTA (n=19) or Endocem Zr (n=20). After 8 weeks, the teeth were extracted and processed with hematoxylin-eosin staining for histologic evaluation. Most of the specimens in both groups developed a calcific barrier at the pulp amputation site and formed an odontoblast layer. However, some of the Endocem Zr specimens showed less calcific barrier formation with a greater inflammatory response and less odontoblast layer formation when compared with the ProRoot MTA specimens. ProRoot MTA and Endocem Zr specimens developed a calcific barrier; however, ProRoot MTA was more biocompatible than Endocem Zr.
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Pediatric Dentistry (소아치과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Conservative Dentistry (보존과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers
Yonsei Authors
Kang, Chung Min(강정민) ORCID logo https://orcid.org/0000-0001-7813-3741
Kim, Seong Oh(김성오) ORCID logo https://orcid.org/0000-0002-8620-1377
Song, Je Seon(송제선) ORCID logo https://orcid.org/0000-0001-8620-5629
Shin, Yoo Seok(신유석) ORCID logo https://orcid.org/0000-0003-1121-2570
Choi, Hyung Jun(최형준) ORCID logo https://orcid.org/0000-0002-3315-6912
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