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Interproximal periodontal defect model in dogs: a pilot study.

Authors
 U-W Jung  ;  Y-Y Chang  ;  S-H Choi  ;  K-S Cho  ;  C-S Kim  ;  Y-J Um 
Citation
 Oral Diseases, Vol.17(1) : 26-32, 2011 
Journal Title
 Oral Diseases 
ISSN
 1354-523X 
Issue Date
2011
Abstract
OBJECTIVE: This study aimed to evaluate the validity of a surgically created interproximal periodontal defect in dogs. MATERIALS AND METHODS: Surgery was performed in the interproximal area between the maxillary second and third premolars in two beagle dogs. Following an incision and reflection of the gingival flap, a 3-mm wide and 5-mm high defect was prepared surgically at the interproximal area. A thorough root planing was performed and the flap was coronally positioned and sutured. The contra-lateral area was served as the control with no surgical intervention. After 8 weeks of healing, the animals were killed and the defect was analysed histometrically and radiographically. RESULTS: The interproximal periodontal defect resembled a naturally occurring defect and mimicked a clinical situation. After healing, the defect showed limited bone (0.89±0.02mm) and cementum regeneration (1.50± 0.48mm). CONCLUSIONS: Within the limitations of this pilot study, the interproximal periodontal defect showed limited bone and cementum regeneration. Thus, it can be considered as a standardized, reproducible defect model for testing new biomaterials.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92578
DOI
10.1111/j.1601-0825.2010.01694.x
Appears in Collections:
1. Journal Papers (연구논문) > 2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실)
Yonsei Authors
김창성(Kim, Chang Sung) ; 엄유정(Um, Yoo Jung) ; 정의원(Jung, Ui Won) ; 조규성(Cho, Kyoo Sung) ; 최성호(Choi, Seong Ho)
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Full Text
http://onlinelibrary.wiley.com/doi/10.1111/j.1601-0825.2010.01694.x/abstract
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