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Characterization of blood using terahertz waves

Authors
 Kiyoung Jeong  ;  Yong-Min Huh  ;  Sang-Hoon Kim  ;  Yeonji Park  ;  Joo-Hiuk Son  ;  Seung Jae Oh  ;  Jin-Suck Suh 
Citation
 Journal of Biomedical Optics, Vol.18(10) : 107008, 2013 
Journal Title
 Journal of Biomedical Optics 
ISSN
 1083-3668 
Issue Date
2013
MeSH
Absorption ; Animals ; Erythrocytes/chemistry* ; Hematologic Tests/methods* ; Male ; Plasma/chemistry* ; Rats ; Rats, Sprague-Dawley ; Refractometry ; Terahertz Spectroscopy/methods*
Keywords
terahertz spectroscopy ; terahertz imaging ; blood spectroscopy ; hematocrit ; red blood cells ; biomedical imaging
Abstract
We show that terahertz (THz) time-domain spectroscopy (TDS) can be used to characterize the blood. The complex optical constants of blood and its constituents, such as water, plasma, and red blood cells (RBCs), were obtained in the THz frequency region. The volume percentage of RBCs in blood was extracted and compared with the conventional RBC counter results. The THz absorption constants are shown to vary linearly with the RBC concentration in both normal saline and whole blood. The excellent linearity between the THz signal and the RBC concentration was also confirmed in a polyurethane resin tube using a THz imaging method. These results demonstrate that THz-TDS imaging can facilitate the quantitative analysis of blood.
Files in This Item:
T201303846.pdf Download
DOI
10.1117/1.JBO.18.10.107008
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Medical Convergence (연의-생공연 메디컬융합연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Hoon(김상훈)
Park, Yeon Ji(박연지)
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Oh, Seung Jae(오승재)
Jeong, Ki Young(정기영)
Huh, Yong Min(허용민) ORCID logo https://orcid.org/0000-0002-9831-4475
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88354
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