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Cohort profile: Korean Urban Rural Elderly (KURE) study, a prospective cohort on ageing and health in Korea

 Namki Hong  ;  Kwang-Joon Kim  ;  Su Jin Lee  ;  Chang Oh Kim  ;  Hyeon Chang Kim  ;  Yumie Rhee  ;  Yoosik Youm  ;  Jin-Young Choi  ;  Hyun-Young Park 
 BMJ OPEN, Vol.9(10) : e031018, 2019 
Journal Title
Issue Date
ageing ; cardiovascular disease ; elderly cohort ; musculoskeletal health
PURPOSE: The Korean Urban Rural Elderly (KURE) cohort was initiated to study the epidemiologic characteristics, physical performance, laboratory and imaging biomarkers and incidence of age-related diseases in an elderly population with respect to both clinical and social aspects to develop preventive and therapeutic strategies for combatting age-related diseases. PARTICIPANTS: A total of 3517 adults aged 65 or older participated in the cohort at baseline from 2012 to 2015, recruited from three urban districts and one rural district in Korea. The second-wave follow-up survey is now being conducted at a 4-year interval from baseline (2016-2019; follow-up rate 71.5%). The data set included detailed information on anthropometric and socioeconomic factors, functional assessments, image scans (plain radiography, dual-energy X-ray absorptiometry and CT), biospecimens (ie, serum, urine and DNA) and social support networks along with the feasibility of linkage to a national claims database. FINDINGS TO DATE: Mean age of participants at entry was 71.9±4.6 years and 67% were women. From the KURE participants enrolled in baseline recruitment, several studies were published in the fields of cardiometabolic diseases, musculoskeletal health and the association between social support network and diseases in ageing. FUTURE PLANS: Participants will be observed actively and passively every 4-5 years and the first follow-up will be completed in 2020. The KURE data set has strength in comprehensive physical function assessments, quantifiable imaging data sets using CT and detailed information regarding the social support networks of participants from a large community-based elderly Korean population.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kwang Joon(김광준) ORCID logo https://orcid.org/0000-0002-5554-8255
Kim, Chang Oh(김창오) ORCID logo https://orcid.org/0000-0002-0773-5443
Kim, Hyeon Chang(김현창) ORCID logo https://orcid.org/0000-0001-7867-1240
Lee, Su Jin(이수진) ORCID logo https://orcid.org/0000-0002-7325-2538
Rhee, Yumie(이유미) ORCID logo https://orcid.org/0000-0003-4227-5638
Choi, Jin Young(최진영) ORCID logo https://orcid.org/0000-0002-9025-6274
Hong, Nam Ki(홍남기) ORCID logo https://orcid.org/0000-0002-8246-1956
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