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Expression patterns of Zfhx1a and Zfhx1b during mouse craniofacial development

 Jeong-Oh Shin  ;  Jong-Min Lee  ;  Jinwoong Bok  ;  Han-Sung Jung 
 Korean Journal of Oral Anatomy (대한구강해부학회지), Vol.39(1) : 1-8, 2018 
Journal Title
 Korean Journal of Oral Anatomy (대한구강해부학회지) 
Issue Date
Zfhx1a ; Zfhx1b, circumvallate papilla ; submandibular gland ; eye
Recent studies have demonstrated that Zfhx1a and Zfhx1b are transcription factors involved in many important signaling pathways. They are known to be essential for neural development, and for the development of other neural-crest-derived tissues. However, much remains to be learned about their expression patterns and functions in the developing tissues of the craniofacial region. We determined the unique expression patterns of Zfhx1a and Zfhx1b during mouse craniofacial development from embryonic day (E) 13.5 to E16.5. In the epithelium of the circumvallate papilla facing the oral cavity, Zfhx1a and Zfhx1b were strongly and weakly expressed, respectively. The epithelial component of the submandibular gland expressed Zfhx1a and Zfhx1b. In the developing eye, Zfhx1a and Zfhx1b were expressed strongly in the retina, and in the anterior region of the lens at E13.5 and E14.5. At E16.5, transcripts of Zfhx1a and Zfhx1b were detected in the developing eyelids. These findings demonstrate the spatial and temporal expression patterns of Zfhx1a and Zfhx1b during mouse craniofacial development.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anatomy (해부학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers
Yonsei Authors
Bok, Jin Woong(복진웅) ORCID logo https://orcid.org/0000-0003-1958-1872
Shin, Jeong Oh(신정오) ORCID logo https://orcid.org/0000-0002-6935-0936
Lee, Jong Min(이종민) ORCID logo https://orcid.org/0000-0002-9466-7644
Jung, Han Sung(정한성) ORCID logo https://orcid.org/0000-0003-2795-531X
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