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Diagnostic performances and interobserver agreement according to observer experience: a comparison study using three guidelines for management of thyroid nodules

Authors
 Jieun Koh  ;  Soo-Yeon Kim  ;  Hye Sun Lee  ;  Eun-Kyung Kim  ;  Jin Young Kwak  ;  Hee Jung Moon  ;  Jung Hyun Yoon 
Citation
 Acta Radiologica, Vol.59(8) : 917-923, 2018 
Journal Title
 Acta Radiologica 
ISSN
 0284-1851 
Issue Date
2018
MeSH
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Observer Variation ; Reproducibility of Results ; Retrospective Studies ; Sensitivity and Specificity ; Thyroid Gland/diagnostic imaging ; Thyroid Nodule/diagnostic imaging* ; Ultrasonography/methods* ; Young Adult
Keywords
Thyroid nodules ; agreement ; diagnosis ; guideline ; ultrasonography
Abstract
Background The differences regarding categorization of thyroid nodules among different guidelines may affect the diagnostic performances and agreement among observers. Purpose To compare the diagnostic performances and agreements between observers with various degree of experience when applying different guidelines for stratifying thyroid nodules using suspicious ultrasonography (US) features. Material and Methods This retrospective study included 370 thyroid nodules (≥10 mm). Four observers, grouped as experienced and inexperienced, evaluated the US features and made final assessments according to the Kim criteria, Thyroid Imaging Reporting and Data System (TIRADS) by Kwak et al., and the 2015 American Thyroid Association (ATA) guideline. Diagnostic performances and agreements among the two groups were compared. Results The Kim criteria shows higher specificity with significantly lower sensitivity when compared to TIRADS and the 2015 ATA guideline (all P < 0.001), regardless of the level of experience. The experienced group showed significantly higher specificity with the Kim criteria and the 2015 ATA guideline compared to the inexperienced group ( P < 0.001), and the inexperienced group showed significantly higher sensitivity using the Kim criteria ( P = 0.002). The experienced group showed significantly higher agreement than the inexperienced group when using TIRADS while higher agreement was seen when using the 2015 ATA guideline for the inexperienced group. Agreement was not significantly different for the Kim criteria according to observer experience. Conclusion The diagnostic performances and agreements show significant differences in risk stratification of thyroid nodules according to the three guidelines using suspicious US features and the level of experience of the observer.
Full Text
http://journals.sagepub.com/doi/abs/10.1177/0284185117744001
DOI
10.1177/0284185117744001
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
곽진영(Kwak, Jin Young) ORCID logo https://orcid.org/0000-0002-6212-1495
김은경(Kim, Eun-Kyung) ORCID logo https://orcid.org/0000-0002-3368-5013
문희정(Moon, Hee Jung) ORCID logo https://orcid.org/0000-0002-5643-5885
윤정현(Yoon, Jung Hyun) ORCID logo https://orcid.org/0000-0002-2100-3513
이혜선(Lee, Hye Sun) ORCID logo https://orcid.org/0000-0001-6328-6948
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163123
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