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Additional Targeted Biopsy in Clinically Suspected Prostate Cancer: Prospective Randomized Comparison between Contrast-Enhanced Ultrasound and Sonoelastography Guidance.

Authors
 Jieun Koh ; Dae Chul Jung ; Sung Joon Hong ; Young Deuk Choi ; Koon-Ho Rha ; Kyung Hwa Han ; Songmi Noh ; Moon Gyu Yoo ; Young Taik Oh 
Citation
 Ultrasound in Medicine and Biology, Vol.41(11) : 2836~2841, 2015 
Journal Title
 Ultrasound in Medicine and Biology 
ISSN
 0301-5629 
Issue Date
2015
Abstract
Our aim was to improve the detection of prostate cancer by evaluating whether contrast-enhanced ultrasound (CEUS) or sonoelastography (SE) is more helpful in guiding targeted biopsy (TB) performed before systematic biopsy (SB). A total of 52 patients suspected of having prostate cancer were prospectively included and randomly assigned to either the CEUS or SE group. Different, independent radiologists performed TB and twelve-core SB. Within each group, cancer detection rates based on core number were compared between SB and TB. We evaluated the effect of TB on core-based cancer detection rates between the CEUS and SE groups. Cancer detection was higher in overall TB cores 16.4% (28/171) than SB cores 11.4% (71/624) in both groups. In the SE group, TB cores revealed higher cancer detection than did SB cores from 4.49% (14/312) to 12.86% (9/70) (p = 0.01). Compared with CEUS, SE may improve detection rates when considering additional TB guidance methods.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/141560
DOI
10.1016/j.ultrasmedbio.2015.06.024
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
1. 연구논문 > 1. College of Medicine > Dept. of Urology
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
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Link
 http://www.sciencedirect.com/science/article/pii/S0301562915004251
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