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A rare case of primary thymic adenocarcinoma mimicking small cell lung cancer

 Eun Na Cho  ;  Hye Sung Park  ;  Tae Hoon Kim  ;  Min Kwang Byun  ;  Hyung Jung Kim  ;  Chul Min Ahn  ;  Yoon Soo Chang 
 Tuberculosis and Respiratory Diseases, Vol.78(2) : 112-119, 2015 
Journal Title
 Tuberculosis and Respiratory Diseases 
Issue Date
Primary thymic adenocarcinoma is a very rare malignancy of the anterior mediastinum with no standardized treatment. A 36-year-old male patient presented with hoarseness over the past 3 months. A chest computed tomography (CT) scan showed an infiltrative mass to the proximal vessels and aortic arch in left upper mediastinum (4.1×3.1×5.4 cm). Brain magnetic resonance imaging (MRI) showed focal lesions, suggesting metastasis in the left frontal lobe. A thoracoscopic biopsy of the mediastinal mass confirmed a primary thymic adenocarcinoma forming a glandular structure with atypia of tumor cells. The patient received four cycles of systemic chemotherapy, consisting of etoposide and cisplatin, with concurrent radiotherapy (6,000 cGy/30 fractions) to the mediastinal lesion and the metastatic brain lesion (4,200 cGy/12 fractions). A follow-up chest CT scan and brain MRI showed a decrease in the size of the left upper mediastinal mass and brain lesion. We report a rare case of the primary thymic adenocarcinoma with a literature review.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
김태훈(Kim, Tae Hoon)
김형중(Kim, Hyung Jung)
박혜성(Park, Heae Surng)
변민광(Byun, Min Kwang)
안철민(Ahn, Chul-Min)
장윤수(Chang, Yoon Soo)
조은나(Cho, Eun Na)
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