1 378

Cited 0 times in

MR thermometry analysis program for laser- or high-intensity focused ultrasound (HIFU)-induced heating at a clinical MR scanner

 Eun Ju Kim  ;  Kiyoung Jeong  ;  Seung Jae Oh  ;  Daehong Kim  ;  Eun Hae Park  ;  Young Han Lee  ;  Jin-Suck Suh 
 JOURNAL OF THE KOREAN PHYSICAL SOCIETY, Vol.65(12) : 2126-2131, 2014 
Journal Title
Issue Date
MR thermometry ; Proton resonance frequency (PRF) ; Laser with GNRs (gold nanorods) ; High-intensity focused ultrasound (HIFU)
Magnetic resonance (MR) thermometry is a noninvasive method for monitoring local temperature change during thermal therapy. In this study, a MR temperature analysis program was established for a laser with gold nanorods (GNRs) and high-intensity focused ultrasound (HIFU)-induced heating MR thermometry. The MR temperature map was reconstructed using the water proton resonance frequency (PRF) method. The temperature-sensitive phase difference was acquired by using complex number subtraction instead of direct phase subtraction in order to avoid another phase unwrapping process. A temperature map-analyzing program was developed and implemented in IDL (Interactive Data Language) for effective temperature monitoring. This one program was applied to two different heating devices at a clinical MR scanner. All images were acquired with the fast spoiled gradient echo (fSPGR) pulse sequence on a 3.0 T GE Discovery MR750 scanner with an 8-channel knee array coil or with a home-built small surface coil. The analyzed temperature values were confirmed by using values simultaneously measured with an optical temperature probe (R2 = 0.996). The temperature change in small samples induced by a laser or by HIFU was analyzed by using a raw data, that consisted of complex numbers. This study shows that our MR thermometry analysis program can be used for thermal therapy study with a laser or HIFU at a clinical MR scanner. It can also be applied to temperature monitoring for any other thermal therapy based on the PRF method.
Full Text
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Medical Convergence (연의-생공연 메디컬융합연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eun Ju(김은주)
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Oh, Seung Jae(오승재)
Lee, Young Han(이영한) ORCID logo https://orcid.org/0000-0002-5602-391X
Jeong, Ki Young(정기영)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.