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Diffusion-tensor magnetic resonance imaging in children with language impairment

Authors
 Jinna Kim  ;  Yong Wook Kim  ;  Chang-il Park  ;  Eun Sook Park  ;  Hyang-Hee Kim  ;  Seung-Koo Lee  ;  Dong Ik Kim 
Citation
 NEUROREPORT, Vol.17(12) : 1279-1282, 2006 
Journal Title
NEUROREPORT
ISSN
 0959-4965 
Issue Date
2006
MeSH
Anisotropy ; Brain Mapping* ; Child ; Child, Preschool ; Diffusion Magnetic Resonance Imaging* ; Female ; Humans ; Image Processing, Computer-Assisted/methods* ; Language Disorders/diagnosis* ; Male
Keywords
children ; di¡usion tensor imaging ; language impairment
Abstract
We evaluated the integrity of the white matter tract using diffusion-tensor magnetic resonance imaging in children with language impairments who exhibited a structurally normal brain on conventional magnetic resonance imaging, and compared it with age-matched normal children. After generating fractional anisotropy and color-coded vector maps, fractional anisotropy values of the major white matter tracts were measured in six locations and compared between the two groups. Compared with the normal control group, the fractional anisotropy values of children with language impairments showed a statistically significant reduction in the genu of the corpus callosum, which is rarely revealed on conventional magnetic resonance images. Our results suggest that delayed maturation of the white matter plays a partial role in the pathophysiological mechanisms of language impairments.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00001756-200608210-00010&LSLINK=80&D=ovft
DOI
10.1097/01.wnr.0000230516.86090.67
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Ik(김동익)
Kim, Yong Wook(김용욱) ORCID logo https://orcid.org/0000-0002-5234-2454
Kim, Jinna(김진아) ORCID logo https://orcid.org/0000-0002-9978-4356
Kim, Hyang Hee(김향희) ORCID logo https://orcid.org/0000-0003-4949-2512
Park, Chang Il(박창일)
Lee, Seung Koo(이승구) ORCID logo https://orcid.org/0000-0001-5646-4072
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/110766
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