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False-positive rate of a "fourth-generation" HIV antigen/antibody combination assay in an area of low HIV prevalence.
- Authors
- Sinyoung Kim ; Jong-Han Lee ; Jun Yong Choi ; June Myung Kim ; Hyon-Suk Kim
- Citation
- Clinical and Vaccine Immunology, Vol.17(10) : 1642-1644, 2010
- Journal Title
- Clinical and Vaccine Immunology
- ISSN
- 1556-6811
- Issue Date
- 2010
- MeSH
- Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antigens, Viral/blood* ; Child ; Child, Preschool ; False Positive Reactions* ; Female ; HIV Antibodies/blood* ; HIV Infections/diagnosis* ; HIV Infections/epidemiology ; Humans ; Immunoassay/methods ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Predictive Value of Tests ; Prevalence ; Retrospective Studies ; Sensitivity and Specificity ; Virology/methods* ; Young Adult
- Abstract
- We retrospectively analyzed the performance of the Architect HIV antigen/antibody (Ag/Ab) combination assay in a tertiary health care center with a situation of low HIV prevalence. The specificity and positive predictive value (PPV) were 99.78% and 31.21%, respectively. However, the specificity and PPV could increase to 99.99% and 89.70% using an arbitrary cutoff value.
- Files in This Item:
- T201002784.pdf Download
- Appears in Collections:
- 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
- Yonsei Authors
-
Kim, Sin Young(김신영)
https://orcid.org/0000-0002-2609-8945
Kim, June Myung(김준명)
Kim, Hyon Suk(김현숙) https://orcid.org/0000-0001-5662-7740
Lee, Jong Han(이종한)
Choi, Jun Yong(최준용) https://orcid.org/0000-0002-2775-3315
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