| 2020 | SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity | AUTOPHAGY |
| 2020 | All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells
| YONSEI MEDICAL JOURNAL |
| 2020 | Ezetimibe ameliorates lipid accumulation during adipogenesis by regulating the AMPK-mTORC1 pathway | FASEB JOURNAL |
| 2020 | Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity | AUTOPHAGY |
| 2019 | NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models | Proceedings of the National Academy of Sciences of the United States of America |
| 2019 | Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possibleinvolvement of ER stress and S6K2 activation
| BMB REPORTS |
| 2019 | Implantable Vascularized Liver Chip for Cross‐Validation of Disease Treatment with Animal Model | ADVANCED FUNCTIONAL MATERIALS |
| 2019 | Repositioning of niclosamide ethanolamine (NEN), an anthelmintic drug, for the treatment of lipotoxicity | FREE RADICAL BIOLOGY AND MEDICINE |
| 2018 | CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes. | PLOS ONE |
| 2018 | The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition.
| FRONTIERS IN ENDOCRINOLOGY |
| 2017 | Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition | AUTOPHAGY |
| 2017 | The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity
| BMB REPORTS |
| 2017 | TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway | AUTOPHAGY |
| 2016 | p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death | FREE RADICAL RESEARCH |
| 2016 | Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis | FREE RADICAL BIOLOGY AND MEDICINE |
| 2016 | SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages | AUTOPHAGY |
| 2015 | The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1 | FREE RADICAL BIOLOGY AND MEDICINE |
| 2015 | Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | p62 prevents carbonyl cyanide m-chlorophenyl hydrazine (CCCP)-induced apoptotic cell death by activating Nrf2 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2013 | Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage
| CELL METABOLISM |
| 2013 | Study of the Signaling Function of Sulfiredoxin and Peroxiredoxin III in Isolated Adrenal Gland: Unsuitability of Clonal and Primary Adrenocortical Cells | METHODS IN ENZYMOLOGY |
| 2012 | Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
| 2012 | Feedback Control of Adrenal Steroidogenesis via H2O2-Dependent, Reversible Inactivation of Peroxiredoxin III in Mitochondria
| MOLECULAR CELL |
| 2012 | Peroxiredoxin III and Sulfiredoxin Together Protect Mice from Pyrazole-Induced Oxidative Liver Injury
| ANTIOXIDANTS & REDOX SIGNALING |
| 2011 | Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver | HEPATOLOGY |
| 2009 | Sestrin 2 Is Not a Reductase for Cysteine Sulfinic Acid of Peroxiredoxins | ANTIOXIDANTS & REDOX SIGNALING |
| 2009 | Induction of Sulfiredoxin via an Nrf2-Dependent Pathway and Hyperoxidation of Peroxiredoxin III in the Lungs of Mice Exposed to Hyperoxia | ANTIOXIDANTS & REDOX SIGNALING |
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