| 2024 | Repositioning of ezetimibe for the treatment of idiopathic pulmonary fibrosis
| EUROPEAN RESPIRATORY JOURNAL |
| 2024 | TAZ deficiency impairs the autophagy-lysosomal pathway through NRF2 dysregulation and lysosomal dysfunction
| INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES |
| 2024 | Magneto-acoustic protein nanostructures for non-invasive imaging of tissue mechanics in vivo
| NATURE MATERIALS |
| 2023 | Fecal microbiota transplantation improves hepatic fibro-inflammation via regulating oxidative stress in experimental NASH
| DIGESTIVE AND LIVER DISEASE |
| 2023 | Association between serum high-density lipoprotein cholesterol and lung function in adults: three cross-sectional studies from US and Korea National Health and Nutrition Examination Survey
| BMJ OPEN RESPIRATORY RESEARCH |
| 2023 | FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner
| CELL DEATH & DISEASE |
| 2022 | Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model
| GASTROENTEROLOGY REPORT |
| 2022 | A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome | HEPATOLOGY |
| 2022 | PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathway
| REDOX BIOLOGY |
| 2022 | Lysosomal Ca 2+-mediated TFEB activation modulates mitophagy and functional adaptation of pancreatic β-cells to metabolic stress
| NATURE COMMUNICATIONS |
| 2021 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) | AUTOPHAGY |
| 2021 | Interplay between Saturated Free Fatty Acids and mmLDL Induces Inflammation in LPS-stimulated Macrophages
| KOREAN CIRCULATION JOURNAL |
| 2020 | SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity | AUTOPHAGY |
| 2020 | Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma?
| CLINICAL AND MOLECULAR HEPATOLOGY |
| 2020 | All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells
| YONSEI MEDICAL JOURNAL |
| 2020 | Ezetimibe ameliorates lipid accumulation during adipogenesis by regulating the AMPK-mTORC1 pathway | FASEB JOURNAL |
| 2020 | Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity | AUTOPHAGY |
| 2019 | NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models | Proceedings of the National Academy of Sciences of the United States of America |
| 2019 | InactivationofSirtuin2protectsmicefromacetaminophen-inducedliverinjury:possibleinvolvementofERstressandS6K2activation
| BMB REPORTS |
| 2019 | Implantable Vascularized Liver Chip for Cross‐Validation of Disease Treatment with Animal Model | ADVANCED FUNCTIONAL MATERIALS |
| 2019 | Repositioningofniclosamideethanolamine(NEN), ananthelminticdrug, for thetreatmentoflipotoxicity | FREE RADICAL BIOLOGY AND MEDICINE |
| 2018 | CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes.
| PLOS ONE |
| 2018 | The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition.
| FRONTIERS IN ENDOCRINOLOGY |
| 2017 | Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition | AUTOPHAGY |
| 2017 | The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity
| BMB REPORTS |
| 2017 | TPT1 (tumor protein, translationally-controlled 1) negatively regulates autophagy through the BECN1 interactome and an MTORC1-mediated pathway | AUTOPHAGY |
| 2016 | p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death | FREE RADICAL RESEARCH |
| 2016 | Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis | FREE RADICAL BIOLOGY AND MEDICINE |
| 2016 | SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages | AUTOPHAGY |
| 2015 | The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1 | FREE RADICAL BIOLOGY AND MEDICINE |
| 2015 | Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | p62 prevents carbonyl cyanide m-chlorophenyl hydrazine (CCCP)-induced apoptotic cell death by activating Nrf2 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2013 | Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage
| CELL METABOLISM |
| 2013 | Study of the Signaling Function of Sulfiredoxin and Peroxiredoxin III in Isolated Adrenal Gland: Unsuitability of Clonal and Primary Adrenocortical Cells | METHODS IN ENZYMOLOGY |
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