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백서두개골 결손부에서 BMP전달체의 골재생효과분석

Other Titles
 The Analysis of Bone regenerative effect with carriers of bone morphogenetic protein in rat calvarial defects 
Authors
 정성원  ;  정지희  ;  최성호  ;  김종관  ;  채중규  ;  조규성  ;  김창성  ;  정의원  ;  채경준 
Citation
 Journal of Korean Academy of Periodontology, Vol.37(4) : 733-742, 2007 
Journal Title
 Journal of Korean Academy of Periodontology (대한치주과학회지) 
ISSN
 0250-3352 
Issue Date
2007
Abstract
Bone morphogenetic proteins have been shown to possess significant osteoinSductive potential, but in order to take advantage of this effect for tissue engineering, carrier systems are essential. Successful carrier systems must enable vascular and cellular invasion, allowing BMP to act as a differentiation factor. The carrier should be reproducible, non-immunogenic, moldable, and space-providing, to define the contours of the resulting bone. The purpose of this study was to review available literature, in comparing various carriers of BMP on rat calvarial defect model. The following conclusions were deduced. 1. Bone regeneration of ACS/BMP, , FFSS/BMP, , MBCP/BMP group were significantly greater than the control groups. 2. Bone density in the ACS/BMP group was greater than that in , FFSS, carrier group. 3. Bone regeneration in FFSS/BMP group was less than in ACS/BMP, , MBCP/BMP group. However, New bone area of carrier group were more greater than that of FFSS/BMP group. ACS, , FFSS, , MBCP were used for carrier of BMP. However, an ideal carrier which was reproducible, non-immunogenic, moldable, and space-providing did not exist. Therefore, further investigation are required in developing a new carrier system.
Files in This Item:
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Kim, Chang Sung(김창성) ORCID logo https://orcid.org/0000-0003-3902-1071
Jung, Ui Won(정의원) ORCID logo https://orcid.org/0000-0001-6371-4172
Cho, Kyoo Sung(조규성) ORCID logo https://orcid.org/0000-0002-6777-5287
Chai, Jung Kyu(채중규)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97808
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