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The Effects of Calcium Phosphate-Chitosan Block Bone Graft on the Periodontal Regeneration in One Wall Intrabony Defects in Beagle Dogs

 Sung Koo Kim  ;  Jung Seok Lee  ;  Seong Ho Choi  ;  Chong Kwan Kim  ;  Yong Keun Lee  ;  Ui Won Jung  ;  Gyung Joon Chae 
 Key Engineering Materials, Vol.342~343 : 393-396, 2007 
Journal Title
 Key Engineering Materials 
Issue Date
This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan block bone and chitosan membrane on the regeneration of 1- wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while experimental group was treated with calcium phosphate chitosan block bone and/or chitosan membrane. All dogs were uneventful healing without any complication. The subjects were sacrificed 8 weeks after the experimental surgery, and a comparative histological and histometric examination was done. Chitosan membrane group significantly enhanced bone regeneration compared to control, CaP-chitosan block bone and combination group. Chitosan membrane remnants were observed in chitosan and combination group, while CaP-chitosan bone materials were resorbed completely. These results suggest that Chitosan membrnae significantly enhanced bone and cementum formation in advanced periodontal defects.
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2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Conservative Dentistry (보존과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Lee, Yong Keun(이용근)
Lee, Jung Seok(이정석)
Jung, Ui Won(정의원) ORCID logo https://orcid.org/0000-0001-6371-4172
Chae, Gyung Joon(채경준)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
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