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산전 스테로이드의 투여가 극소 저출생 체중아의 생후 초기 수분 평형 상태에 미치는 영향

Other Titles
 Effects of Antenatal Steroid on Postnatal Fluid Balance in Very Low Birth Weight (VLBW) Infants during the First Week of Life. 
 김정은  ;  최은나  ;  허경  ;  김명준  ;  이철  ;  박국인  ;  박민수  ;  남궁란 
 Journal of the Korean Society of Neonatology, Vol.14(2) : 170-177, 2007 
Journal Title
Journal of the Korean Society of Neonatology(대한신생아학회지)
Issue Date
Steroid ; Very low birth weight ; Insensible water loss ; Fluid balance
Purpose:Antenatal steroid (AS) may result in lower insensible water loss (IWL), and higher urine output (UO) in early life. We examined if the postnatal fluid balance differed between infants exposed to AS or not (control) in VLBW infants. Methods:Fifty-four VLBW infants were grouped into AS (n=24) or control (n=30). Fluid intake, UO, IWL and maximal % of weight loss on day 1, day 2, day 3 and day 7 after birth were analyzed. Daily maintenance fluid was determined in each infants by calculation of insensible water loss (IWL=[intake-output]-△wt) and UO. Results:Fluid intake (AS vs control; 117.2±33.9 vs 126.0±29.6 mL/kg/d, P=0.315), IWL (28.1±23.7 vs 21.1±20.5 P=0.248), UO and maximal % of weight loss on day 7 were not different between groups: similar findings were observed on day 1, day 2, and day 3 after birth. Neonatal morbidities and clinical relevant factors were not different between groups. The duration of assisted ventilation was shorter in the AS than in the control (10.8±9.2 vs 27.6±26.2, P=0.002). However, the difference disappeared after adjustment for RDS severity and oxygenation index. Conclusion:VLBW infants exposed to AS did not have an alteration in postnatal fluid balance during the first week of life, when given fluid based on needs reflected by IWL and UO. The decreased need for assisted ventilation in the AS group may be related to the effects of steroid on fetal lung fluid absorption or maturity, but not on postnatal fluid balance
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1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myung Joon(김명준) ORCID logo https://orcid.org/0000-0002-4608-0275
Kim, Jeong Eun(김정은)
Namgung, Ran(남궁란) ORCID logo https://orcid.org/0000-0001-7182-9535
Park, Kook In(박국인) ORCID logo https://orcid.org/0000-0001-8499-9293
Park, Min Soo(박민수) ORCID logo https://orcid.org/0000-0002-4395-9938
Lee, Chul(이철)
Choi, Eun Na(최은나)
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