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Effects of a chitosan membrane coated with polylactic and polyglycolic acid on bone regeneration in a rat calvarial defect

Authors
 Ui-Won Jung  ;  Kun-Young Song  ;  Seong-Ho Choi  ;  Chong-Kwan Kim  ;  Kyoo-Sung Cho  ;  Yong-Keun Lee  ;  Chang-Sung Kim 
Citation
 BIOMEDICAL MATERIALS, Vol.2(3) : 101-105, 2007 
Journal Title
 BIOMEDICAL MATERIALS 
ISSN
 1748-6041 
Issue Date
2007
Abstract
The purpose of this study was to evaluate the effects of a chitosan membrane coated with polylactic and polyglycolic acid (PLGA) on bone regeneration in a rat calvarial defect. Surgical implantation of chitosan membranes resulted in enhanced local bone formation at both 2 and 8 weeks. In conclusion, the chitosan membrane coated with PLGA had a significant potential to induce bone formation in the rat calvarial defect model. Within the selected PLGA dose range and observation intervals, there appeared to be no meaningful differences in bone formation.
Full Text
http://iopscience.iop.org/1748-605X/2/3/S03/
DOI
10.1088/1748-6041/2/3/S03
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Kim, Chang Sung(김창성) ORCID logo https://orcid.org/0000-0003-3902-1071
Lee, Yong Keun(이용근)
Cho, Kyoo Sung(조규성) ORCID logo https://orcid.org/0000-0002-6777-5287
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/95716
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