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Chlamydia trachomatis 검출을 위한 실시간 중합효소연쇄반응법 2종의 평가

Other Titles
 Evaluation of two real-time PCR assays for the detection of Chlamydia trachomatis 
Authors
 이은영  ;  김신영  ;  김현숙 
Citation
 Journal of Laboratory Medicine and Quality Assurance (임상검사와 정도관리), Vol.33(1) : 43-47, 2011 
Journal Title
Journal of Laboratory Medicine and Quality Assurance(임상검사와 정도관리)
ISSN
 1225-097X 
Issue Date
2011
Keywords
Chlamydia trachomatis ; Real-time polymearse chain reaction ; comparison
Abstract
BackgroundChlamydia trachomatis is common etiological agent of sexual transmitted disease. We evaluated two real-time PCR assays for the detection of C. trachomatis; Cobas TaqMan CT test v2.0 (Roche Diagnostics, Switzerland) and AdvanSure CT/NG real-time PCR (LG Life Sciences, Korea). And we compared performance of two real-time PCR assays with Cobas Amplicor CT test (Roche Diagnostics, Switzerland).Methods:Seventy-nine cervical swab specimens collected from patients with suspected C. trachomatis infection were tested using CTM CT, ADVANSURE, and AMPLICOR for the detection of C. trachomatis.

Results:Twenty-five (31.6%) samples showed positive results in all three assays. The positive and negative concordance rates among three assays were 100%

Conclusion:CTM CT and ADVANSURE showed excellent agreement with AMPLICOR. Therefore, these assays were reliable for the evaluation of C. trachomatis infection.
Files in This Item:
T201103386.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sin Young(김신영) ORCID logo https://orcid.org/0000-0002-2609-8945
Kim, Hyon Suk(김현숙) ORCID logo https://orcid.org/0000-0001-5662-7740
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94263
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