3 309

Cited 7 times in

Diffuse microcalcifications only of the thyroid gland seen on ultrasound: clinical implication and diagnostic approach.

Authors
 Jung Hyun Yoon  ;  Eun-Kyung Kim  ;  Eun Ju Son  ;  Hee Jung Moon  ;  Jin Young Kwak 
Citation
 ANNALS OF SURGICAL ONCOLOGY, Vol.18(10) : 2899-2906, 2011 
Journal Title
 ANNALS OF SURGICAL ONCOLOGY 
ISSN
 1068-9265 
Issue Date
2011
MeSH
Adolescent ; Adult ; Biopsy, Fine-Needle ; Calcinosis/pathology* ; Carcinoma, Papillary/diagnostic imaging* ; Carcinoma, Papillary/pathology ; Carcinoma, Papillary/surgery ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Thyroid Gland/diagnostic imaging* ; Thyroid Gland/pathology* ; Thyroid Gland/surgery ; Thyroid Neoplasms/diagnostic imaging* ; Thyroid Neoplasms/pathology ; Thyroid Neoplasms/surgery ; Thyroidectomy ; Thyroiditis, Autoimmune/diagnostic imaging* ; Thyroiditis, Autoimmune/pathology ; Thyroiditis, Autoimmune/surgery ; Ultrasonography ; Young Adult
Keywords
Thyroid Cancer ; Papillary Thyroid Carcinoma ; Thyroid Nodule ; Hashimoto Thyroiditis ; Pathologic Lymph Node
Abstract
BACKGROUND: To evaluate the clinical implications and diagnostic approach of lesions showing only diffuse microcalcifications on thyroid ultrasound (US). METHODS: From January 2004 to January 2011, a total of 31 patients had lesions showing diffuse microcalcifications alone on thyroid US. Among them, 26 patients (M:F ratio 4:22; mean age 37.5 years, range 15-56 years) who had underwent US-guided fine-needle aspiration biopsy (US-FNAB), subsequent surgery, or follow-up US after 1 year after initial US-FNAB were included. Histopathologic results from surgery or US-FNAB were considered as standard reference. Clinical and US features were compared to standard reference. RESULTS: Of the disease of 26 patients, 16 (61.5%) were diagnosed as malignancy and 10 (38.5%) as benign. Seventeen (65.4%) of the 26 patients included were diagnosed as having Hashimoto thyroiditis (HT) on a clinical basis. Eight (80.0%) of the 10 benign lesions were diagnosed as benign on initial US-FNAB, and the remaining 2 lesions (20.0%) were nondiagnostic. All malignant lesions were diagnosed as suspicious for papillary thyroid carcinoma (PTC) or PTC by US-FNAB. Of the US features, presence of pathologic lymph nodes were significantly higher in malignant disease compared to benign findings, 10 (62.5%) to 0 (0.0%) (P = 0.003). CONCLUSIONS: Diffuse microcalcifications only lesions of the thyroid show high prevalence of PTC and lymphocytic thyroiditis. US-FNAB shows an acceptable performance in lesions showing microcalcifications only on thyroid US.
Full Text
http://link.springer.com/article/10.1245%2Fs10434-011-1717-0
DOI
10.1245/s10434-011-1717-0
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Jin Young(곽진영) ORCID logo https://orcid.org/0000-0002-6212-1495
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Moon, Hee Jung(문희정) ORCID logo https://orcid.org/0000-0002-5643-5885
Son, Eun Ju(손은주) ORCID logo https://orcid.org/0000-0002-7895-0335
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94238
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links