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Performance of hand-held whole-breast ultrasound based on BI-RADS in women with mammographically negative dense breast

Authors
 Ji Hyun Youk  ;  Eun-Kyung Kim  ;  Min Jung Kim  ;  Jin Young Kwak  ;  Eun Ju Son 
Citation
 European Radiology, Vol.21(4) : 667-675, 2011 
Journal Title
 European Radiology 
ISSN
 0938-7994 
Issue Date
2011
Abstract
OBJECTIVE: To assess the performance of breast ultrasound based on BI-RADS final assessment categories in women with mammographically negative dense breast. METHODS: Of 3,820 cases with mammographically negative dense breast and subsequent hand-held bilateral whole-breast ultrasound, a total of 1,507 cases in 1,046 women who had biopsy or at least 2-year follow-up ultrasound constituted the basis of this retrospective study. Cancer rate of each sonographic BI-RADS category was determined and medical audit was performed separately in screening-general, screening-treated, and diagnostic group. RESULTS: A total of 43 cases (2.9%) were confirmed as malignancy. Cancer rate among BI-RADS categories was significantly different (p < 0.0001). Among three groups, the cancer rate was significantly different (p < 0.0001) and the highest in diagnostic group (15.8%, 22 of 139). Abnormal interpretation rate, PPV of biopsy performed, cancer detection rate, and rate of early stage cancer, and the size of invasive cancer were significantly different among three groups and the highest in diagnostic group. Regarding cancer characteristics, the proportion of advanced cancer was the highest in diagnostic group. CONCLUSION: Breast ultrasound based on BI-RADS as an adjunctive to negative mammography can be useful for predicting malignancy in women with dense breast.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92756
Full Text
http://link.springer.com/article/10.1007%2Fs00330-010-1955-8
DOI
10.1007/s00330-010-1955-8
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
곽진영(Kwak, Jin Young)
김민정(Kim, Min Jung) ORCID logo https://orcid.org/0000-0003-4949-1237
김은경(Kim, Eun-Kyung) ORCID logo https://orcid.org/0000-0002-3368-5013
손은주(Son, Eun Ju)
육지현(Youk, Ji Hyun) ORCID logo https://orcid.org/0000-0002-7787-780X
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