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항응고제 복용 환자에서 저분자량 헤파린을 사용한 구강 내 소수술

Other Titles
 Oral Surgery using Low-molecular-weight Heparin in the Anticoagulated Patients 
 황세영 ; 윤희정 ; 박원서 ; 김형준 ; 김기덕 ; 정복영 ; 방난심 
 대한치과마취과학회지, Vol.12(2) : 99~104, 2012 
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Issue Date
Anticoagulation therapy with warfarin sodium is used to reduce the risk of thromboembolic events in patients with valvular heart disease, prosthetic heart valve, recurrent myocardiac infarction, etc. To keep anticoagulation state and minimize bleeding risk, patients with high risk of thromboembolism have been usually hospitalized for heparinization before oral surgery like extraction. However, this protocol requires time and high expense because of the long period of hospitalization and this is why low-molecular-weight heparin (LMWH) therapy is receiving attention in medical field as well as dentistry. LMWH has several advantages over unfractionated heparin (UFH) including predictable anticoagulant response which makes coagulation monitoring unnecessary in most patients and longer half-life than heparin which enables the patients to give themselves a subcutaneous injection once or twice daily. These advantages of LMWH make patients get oral surgery on an outpatient basis so that they can save time and cost. This case report introduces the use of LMWH in dental surgery and suggests proper use of LMWH. Though LMWH bridging therapy is widely used most of the previous studies are observational studies. Therefore randomized controlled trials are necessary to evaluate the safety and efficacy of LMWH bridging therapy.
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1. 연구논문 > 2. College of Dentistry > Dept. of Advanced General Dentistry
1. 연구논문 > 2. College of Dentistry > Dept. of Oral and Maxillofacial Surgery
Yonsei Authors
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