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In vitro and in vivo characteristics of stem cells derived from the periodontal ligament of human deciduous and permanent teeth

DC FieldValueLanguage
dc.contributor.author김성오-
dc.contributor.author김승혜-
dc.contributor.author김창성-
dc.contributor.author손흥규-
dc.contributor.author송제선-
dc.contributor.author이제호-
dc.contributor.author정한성-
dc.contributor.author최형준-
dc.date.accessioned2014-12-19T17:43:34Z-
dc.date.available2014-12-19T17:43:34Z-
dc.date.issued2012-
dc.identifier.issn1937-3341-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/91938-
dc.description.abstractIn many studies, adult stem cells have been found in human periodontal ligament (PDL), but in most cases they were found in the permanent teeth. The aim of the present study was to characterize stem cells from the PDL of deciduous teeth (dPDLSCs) and compare them with those from the PDL of permanent teeth (pPDLSCs). Stem cell markers were examined by a flow cytometric analysis. The results of in vitro differentiation into adipogenic and osteogenic lineages were analyzed by histochemical staining and quantitative reverse transcription-polymerase chain reaction (RT-PCR). The results of in vivo transplantation were analyzed by histological staining, immunohistochemical staining, and quantitative RT-PCR. There were no significant differences in the proliferation rate, cell cycle distribution, expressions of stem cell markers such as Stro-1 and CD146, or in vitro differentiation. The pPDLSC transplants made more typical cementum/PDL-like tissues and expressed more cementum/PDL-related genes (CP23 and collagen XII) than did the dPDLSC transplants. Together, these results suggest that pPDLSCs are better candidates for use in reconstructing periodontium.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfTissue Engineering Part A-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleIn vitro and in vivo characteristics of stem cells derived from the periodontal ligament of human deciduous and permanent teeth-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Periodontology (치주과학)-
dc.contributor.googleauthorJe Seon Song-
dc.contributor.googleauthorSeong-Oh Kim-
dc.contributor.googleauthorSeung-Hye Kim-
dc.contributor.googleauthorHyung-Jun Choi-
dc.contributor.googleauthorHeung-Kyu Son-
dc.contributor.googleauthorHan-Sung Jung-
dc.contributor.googleauthorChang-Sung Kim-
dc.contributor.googleauthorJae-Ho Lee-
dc.identifier.doi10.1089/ten.tea.2011.0318-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00577-
dc.contributor.localIdA01041-
dc.contributor.localIdA02005-
dc.contributor.localIdA02058-
dc.contributor.localIdA03134-
dc.contributor.localIdA03758-
dc.contributor.localIdA04216-
dc.contributor.localIdA00664-
dc.relation.journalcodeJ02735-
dc.identifier.urlhttp://online.liebertpub.com/doi/full/10.1089/ten.tea.2011.0318-
dc.contributor.alternativeNameKim, Seong Oh-
dc.contributor.alternativeNameKim, Seung Hye-
dc.contributor.alternativeNameKim, Chang Sung-
dc.contributor.alternativeNameSon, Heung Kyu-
dc.contributor.alternativeNameSong, Je Seon-
dc.contributor.alternativeNameLee, Jae Ho-
dc.contributor.alternativeNameJung, Han Sung-
dc.contributor.alternativeNameChoi, Hyung Jun-
dc.contributor.affiliatedAuthorKim, Seong Oh-
dc.contributor.affiliatedAuthorKim, Chang Sung-
dc.contributor.affiliatedAuthorSon, Heung Kyu-
dc.contributor.affiliatedAuthorSong, Je Seon-
dc.contributor.affiliatedAuthorLee, Jae Ho-
dc.contributor.affiliatedAuthorJung, Han Sung-
dc.contributor.affiliatedAuthorChoi, Hyung Jun-
dc.contributor.affiliatedAuthorKim, Seung Hye-
dc.citation.volume18-
dc.citation.number19-20-
dc.citation.startPage2040-
dc.citation.endPage2051-
dc.identifier.bibliographicCitationTissue Engineering Part A, Vol.18(19-20) : 2040-2051, 2012-
dc.description.scptc20-
dc.date.scptcdate2018-12-23-
Appears in Collections:
1. Journal Papers (연구논문) > 2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실)
1. Journal Papers (연구논문) > 2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실)
1. Journal Papers (연구논문) > 2. College of Dentistry (치과대학) > Dept. of Pediatric Dentistry (소아치과학교실)

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