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Cancer Diagnosis by Terahertz Molecular Imaging Technique

Authors
 Seung Jae Oh  ;  Yong-Min Huh  ;  Jin-Suck Suh  ;  Jihye Choi  ;  Seungjoo Haam  ;  Joo-Hiuk Son 
Citation
 JOURNAL OF INFRARED MILLIMETER AND TERAHERTZ WAVES, Vol.33(1) : 74-81, 2012 
Journal Title
JOURNAL OF INFRARED MILLIMETER AND TERAHERTZ WAVES
ISSN
 1866-6892 
Issue Date
2012
Keywords
Terahertz molecular imaging ; Terahertz imaging ; Nanoprobe ; Nanoparticle
Abstract
We obtained the diagnostic images of cancerous tumors by employing the THz molecular imaging (TMI) technique which measured the THz response change by surface plasmon resonance induced on the surface of nanoparticles with a irradiation of near-infrared (NIR) beam. To demonstrate the principle of the TMI technique, THz images of tissues with nanoprobes were observed and compared with THz only images. The sensitivity of TMI was further enhanced by adopting a THz differential measurement technique, which was realized by modulating the NIR beams. By employing this differential TMI technique, the diagnostic images of cancerous tumors were obtained ex vivo and in vivo in the preclinical stage. These images indicated the feasibility of applying the differential TMI technique in the clinical stage.
Full Text
http://link.springer.com/article/10.1007/s10762-011-9847-9#
DOI
10.1007/s10762-011-9847-9
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Oh, Seung Jae(오승재)
Huh, Yong Min(허용민) ORCID logo https://orcid.org/0000-0002-9831-4475
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90857
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