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Comparison of arterial stiffness indices measured by the Colins and SphygmoCor systems

 Jong-Chan Youn  ;  Jong-Youn Kim  ;  Sungha Park  ;  Jisun Kwon  ;  Hye Sun Lee  ;  Dong-Ho Shin  ;  Sang-Hak Lee  ;  Seok-Min Kang  ;  Nak Hoon Son  ;  Yangsoo Jang 
 HYPERTENSION RESEARCH, Vol.35(12) : 1180-1184, 2012 
Journal Title
Issue Date
Adult ; Aged ; Aged, 80 and over ; Blood Pressure ; Female ; Humans ; Male ; Middle Aged ; Pulse Wave Analysis ; ROC Curve ; Vascular Stiffness*
arterial stiffness ; augmentation index ; Colins ; pulse wave velocity ; SphygmoCor
Arterial stiffness is a known independent predictor of cardiovascular mortality. The Colins system is an easy device and has gained widespread use, but the cutoff value for high-risk central arterial stiffness is not well established. We investigated the correlation between arterial stiffness measured by the Colins system with conventional measurements from the SphygmoCor system. Arterial pulse wave velocity (PWV) and augmentation indices (AIs) were measured on a single visit using two different devices in 948 patients with hypertension or coronary artery disease. Strong positive correlations were observed for PWV values measured by the SphygmoCor and Colins systems. The Colins system measurements accurately predicted high-risk central arterial stiffness, defined as carotid-femoral PWV≥12 m s(-1), with an area under the receiver-operating characteristic curve (AUC) of 0.884 (heart-femoral PWV, hfPWV) and 0.830 (brachial-ankle PWV, baPWV) in the training set (N=664). The cutoff values, 11.18 (hfPWV) and 16.17 m s(-1) (baPWV), showed good discrimination in the validation set (N=284), with sensitivity of 83.3 (hfPWV) and 76.0% (baPWV), and specificity of 74.9 (hfPWV) and 82.6% (baPWV). The SphygmoCor and Colins AI systems also showed moderate positive correlation. The Colins AI system better predicted high-risk central pulse pressure as defined by pulse pressure≥50 mm Hg (AUC: Colins, 0.765; SphygmoCor, 0.692; P=0.011). Arterial stiffness measured by the Colins system showed strong positive correlation and agreement with the SphygmoCor system measurement. Cutoff values for high-risk central arterial stiffness in the Colins system need further validation in a prospective study.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
Yonsei Authors
Kang, Seok Min(강석민) ORCID logo https://orcid.org/0000-0001-9856-9227
Kwon, Ji Sun(권지선)
Kim, Jong Youn(김종윤) ORCID logo https://orcid.org/0000-0001-7040-8771
Park, Sung Ha(박성하) ORCID logo https://orcid.org/0000-0001-5362-478X
Son, Nak Hoon(손낙훈) ORCID logo https://orcid.org/0000-0002-6192-8852
Shin, Dong Ho(신동호) ORCID logo https://orcid.org/0000-0002-7874-5542
Youn, Jong Chan(윤종찬)
Lee, Sang Hak(이상학) ORCID logo https://orcid.org/0000-0002-4535-3745
Lee, Hye Sun(이혜선) ORCID logo https://orcid.org/0000-0001-6328-6948
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
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