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Molecular sensing for biomarkers of invasive cancer cells using localized surface plasmon resonance
DC Field | Value | Language |
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dc.contributor.author | 구민희 | - |
dc.contributor.author | 서진석 | - |
dc.contributor.author | 양재문 | - |
dc.contributor.author | 허용민 | - |
dc.date.accessioned | 2014-12-18T09:36:04Z | - |
dc.date.available | 2014-12-18T09:36:04Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1083-3668 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88476 | - |
dc.description.abstract | In this study, we describe the development of cancer biomarker-sensitive nanobiosensor based on localized surface plasmon resonance (LSPR) that enabling recognition for proteolytic activity of membrane type 1 matrix metalloproteinase (MT1-MMP) anchored on invasive cancer cells. First of all, we prepared biomarker-detectable substrate based on gold nanorods (GNRs) using nanoparticle adsorption method. The sensitivity of sensing chip was confirmed using various solvents that having different refractive indexes. Subsequently, MT1-MMP-specific cleavable peptide was conjugated onto surface of GNRs and molecular sensing about proteolytic activity was conducted using MT1-MMP and cell lysates. Collectively, we developed biomarker detectable sensor, which allows for the effective detection of proteolytic activity about MT1-MMP extracted from invasive cancer cells. © (2013) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | JOURNAL OF BIOMEDICAL OPTICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Biomarkers, Tumor/analysis* | - |
dc.subject.MESH | Biosensing Techniques/methods* | - |
dc.subject.MESH | Cell Line, Tumor | - |
dc.subject.MESH | Gold/chemistry | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immobilized Proteins/chemistry | - |
dc.subject.MESH | Immobilized Proteins/metabolism | - |
dc.subject.MESH | Matrix Metalloproteinase 14/chemistry | - |
dc.subject.MESH | Matrix Metalloproteinase 14/metabolism | - |
dc.subject.MESH | Nanotubes/chemistry | - |
dc.subject.MESH | Neoplasm Invasiveness | - |
dc.subject.MESH | Proteolysis | - |
dc.subject.MESH | Surface Plasmon Resonance/methods* | - |
dc.title | Molecular sensing for biomarkers of invasive cancer cells using localized surface plasmon resonance | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Yoochan Hong | - |
dc.contributor.googleauthor | Minhee Ku | - |
dc.contributor.googleauthor | Jin-Suck Suh | - |
dc.contributor.googleauthor | Yong-Min Huh | - |
dc.contributor.googleauthor | Dae Sung Yoon | - |
dc.contributor.googleauthor | Jaemoon Yang | - |
dc.identifier.doi | 10.1117/12.2018326 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00191 | - |
dc.contributor.localId | A01916 | - |
dc.contributor.localId | A04359 | - |
dc.contributor.localId | A02315 | - |
dc.relation.journalcode | J01269 | - |
dc.identifier.eissn | 1560-2281 | - |
dc.identifier.pmid | 24297057 | - |
dc.identifier.url | http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1699949 | - |
dc.subject.keyword | Biomarkers, Tumor/analysis* | - |
dc.subject.keyword | Biosensing Techniques/methods* | - |
dc.subject.keyword | Cell Line, Tumor | - |
dc.subject.keyword | Gold/chemistry | - |
dc.subject.keyword | Humans | - |
dc.subject.keyword | Immobilized Proteins/chemistry | - |
dc.subject.keyword | Immobilized Proteins/metabolism | - |
dc.subject.keyword | Matrix Metalloproteinase 14/chemistry | - |
dc.subject.keyword | Matrix Metalloproteinase 14/metabolism | - |
dc.subject.keyword | Nanotubes/chemistry | - |
dc.subject.keyword | Neoplasm Invasiveness | - |
dc.subject.keyword | Proteolysis | - |
dc.subject.keyword | Surface Plasmon Resonance/methods* | - |
dc.contributor.alternativeName | Ku, Min Hee | - |
dc.contributor.alternativeName | Suh, Jin Suck | - |
dc.contributor.alternativeName | Yang, Jae Moon | - |
dc.contributor.alternativeName | Huh, Yong Min | - |
dc.contributor.affiliatedAuthor | Ku, Min Hee | - |
dc.contributor.affiliatedAuthor | Suh, Jin Suck | - |
dc.contributor.affiliatedAuthor | Huh, Yong Min | - |
dc.contributor.affiliatedAuthor | Yang, Jae Moon | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 8879 | - |
dc.citation.startPage | 88790 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOMEDICAL OPTICS, Vol.8879 : 88790, 2013 | - |
dc.identifier.rimsid | 34055 | - |
dc.type.rims | ART | - |
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