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Variability of Shear Wave Velocity using Different Frequencies in Acoustic Radiation Force Impulse (ARFI) Elastography: A Phantom and Normal Liver Study

 S. Chang  ;  M.-J. Kim  ;  J. Kim  ;  M.-J. Lee 
 ULTRASCHALL IN DER MEDIZIN, Vol.34(3) : 260-265, 2013 
Journal Title
Issue Date
Adult ; Elasticity Imaging Techniques/instrumentation* ; Elasticity Imaging Techniques/methods* ; Female ; Humans ; Image Enhancement/instrumentation* ; Image Enhancement/methods* ; Image Interpretation, Computer-Assisted/instrumentation* ; Image Interpretation, Computer-Assisted/methods* ; Liver/diagnostic imaging* ; Male ; Phantoms, Imaging* ; Reference Values ; Sensitivity and Specificity ; Young Adult
acoustic radiation force impulse-imaging ; phantom ; liver ; variability
Purpose: To assess the variability of shear wave velocity (SWV) from acoustic radiation force impulse (ARFI) elastography at various depths using different frequencies.

Materials and Methods: ARFI elastography of the elasticity phantom and normal liver was performed at different depths (2 – 5 cm) with convex (1 – 4 MHz) and linear (4 – 9 MHz) probes. Ten valid SWV measurements at each depth were performed. This was repeated ten times with the phantom and performed in eight healthy volunteers (M:F = 3:5, age 20 – 34 years). The mean value and standard deviation of the SWV were calculated.

Results: In both the phantom and liver, the mean velocities as measured by two probes at the same depth were different. Variabilities of SWV at different depths were also different for the two probes. The depth with lower variability in the phantom was 4 and 5 cm with a convex probe and 2 cm with a linear probe. In the liver, the depth with lower variability was 4 cm with a convex probe and 3 and 4 cm with a linear probe. In comparative analysis of the two probes, the linear probe displayed a lower variability at a depth of 2 and 3 cm in the phantom and at 3 cm in the liver, whereas the convex probe displayed a lower variability at a depth of 4 cm in both the phantom and the liver.

Conclusion: SWVs and variability are different depending on the depth and the frequency used. SWVs with a low frequency probe had a tendency to be higher at the same depth. To reduce variability of SWV, a high frequency probe is recommended for a depth of 2 – 3 cm, and a low frequency probe is recommended for a depth of 4 – 5 cm.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
Kim, Myung Joon(김명준) ORCID logo https://orcid.org/0000-0002-4608-0275
Kim, Ji Eun(김지은)
Lee, Mi-Jung(이미정) ORCID logo https://orcid.org/0000-0003-3244-9171
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