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A Highly Crystalline Manganese-Doped Iron Oxide Nanocontainer with Predesigned Void Volume and Shape for Theranostic Applications

Authors
 Vu Ngoc Phan  ;  Eun-Kyung Lim  ;  Taekhoon Kim  ;  Minsik Kim  ;  Yuna Choi  ;  Byeongyoon Kim  ;  Myounghoon Lee  ;  Aram Oh  ;  Juhong Jin  ;  Youngjoo Chae  ;  Hionsuck Baik  ;  Jin-Suck Suh  ;  Seungjoo Haam  ;  Yong-Min Huh  ;  Kwangyeol Lee 
Citation
 ADVANCED MATERIALS, Vol.25(23) : 3202-3208, 2013 
Journal Title
 ADVANCED MATERIALS 
ISSN
 0935-9648 
Issue Date
2013
MeSH
Animals ; Antibiotics, Antineoplastic/administration & dosage ; Cell Line ; Crystallization ; Doxorubicin/administration & dosage ; Drug Carriers/chemistry ; Ferric Compounds/chemistry* ; Humans ; Hydrogen-Ion Concentration ; Liver Neoplasms/drug therapy ; Manganese/chemistry ; Mice ; Nanostructures/chemistry* ; Particle Size
Keywords
Animals ; Antibiotics, Antineoplastic/administration & dosage ; Cell Line ; Crystallization ; Doxorubicin/administration & dosage ; Drug Carriers/chemistry ; Ferric Compounds/chemistry* ; Humans ; Hydrogen-Ion Concentration ; Liver Neoplasms/drug therapy ; Manganese/chemistry ; Mice ; Nanostructures/chemistry* ; Particle Size
Abstract
Hollow Mn-doped iron oxide nanocontainers, formed by a novel one-pot synthetic process, fulfill the dual requirements of delivering an effective dose of an anticancer drug to tumor tissue and enabling image-contrast monitoring of the nanocontainer fate through T2 -weighted magnetic resonance imaging, thereby determining the optimal balance between diagnostic and therapeutic moieties in an all-in-one theranostic nanoplatform
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/adma.201300525/abstract
DOI
10.1002/adma.201300525
Appears in Collections:
5. Research Institutes (연구소) > Institute for Medical Convergence (연의-생공연 메디컬융합연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Lim, Eun Kyung(임은경)
Huh, Yong Min(허용민) ORCID logo https://orcid.org/0000-0002-9831-4475
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86818
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