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Double-ligand modulation for engineering magnetic nanoclusters

Authors
 Bongjune Kim  ;  Jaemoon Yang  ;  Eun-Kyung Lim  ;  Joseph Park  ;  Jin-Suck Suh  ;  Hyo Seon Park  ;  Yong-Min Huh  ;  Seungjoo Haam 
Citation
 NANOSCALE RESEARCH LETTERS, Vol.8(1) : 104, 2013 
Journal Title
 NANOSCALE RESEARCH LETTERS 
ISSN
 1931-7573 
Issue Date
2013
Keywords
Magnetic nanoparticle ; Double-ligand modulation ; Nanoemulsion ; Magnetic nanocluster ; Magnetic resonance imaging
Abstract
Magnetic nanoclusters (MNCs) are agglomerated individual magnetic nanoparticles (MNPs) that show great promise in increasing magnetic resonance imaging (MRI) sensitivity. Here, we report an effective strategy to engineer MNCs based on double-ligand modulation to enhance MRI sensitivity. The oleic acid-coated individual MNPs self-assembled and then were enveloped by polysorbate 80, using a nanoemulsion method to prepare MNCs. By modulating the amounts of the two ligands, and thus the size and magnetic content of the resultant MNCs, we were able to enormously improve MRI sensitivity.
Files in This Item:
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DOI
10.1186/1556-276X-8-104
Appears in Collections:
5. Research Institutes (연구소) > Institute for Medical Convergence (연의-생공연 메디컬융합연구소) > 1. Journal Papers
5. Research Institutes (연구소) > Yonsei Integrative Research Institute for Cerebral & Cardiovascular Disease (뇌심혈관질환융합연구사업단) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Yang, Jae Moon(양재문) ORCID logo https://orcid.org/0000-0001-7365-0395
Lim, Eun Kyung(임은경)
Huh, Yong Min(허용민) ORCID logo https://orcid.org/0000-0002-9831-4475
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86579
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