Yonsei Advanced Medical Science Research and Education (첨단의과학교육연구단)

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Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Hui Kwon Kim ; Seonwoo Min ; Myungjae Song ; Soobin Jung ; Jae Woo Choi ; You... NATURE BIOTECHNOLOGY, Vol.36(3) : 239-241, 2018

Sequence-specific prediction of the efficiencies of adenine and cytosine...

Myungjae Song ; Hui Kwon Kim ; Sungtae Lee ; Younggwang Kim ; Sang-Yeon Seo ;... NATURE BIOTECHNOLOGY, Vol.38(9) : 1037-1043, 2020-09

Antigen-Specific IFN-γ/IL-17-Co-Producing CD4 + T-Cells Are the Determin...

Han-Gyu Choi ; Kee Woong Kwon ; Seunga Choi ; Yong Woo Back ; Hye-Soo Park ; ... VACCINES, Vol.8(2) : 300, 2020-06
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Issue DateTitleJournal Title
2022BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis SCIENTIFIC REPORTS
2022Novel Antibacterial Activity of Febuxostat, an FDA-Approved Antigout Drug against Mycobacterium tuberculosis InfectionANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2022Host-directed anti-mycobacterial activity of colchicine, an anti-gout drug, via strengthened host innate resistance reinforced by the IL-1β/PGE 2 axisBRITISH JOURNAL OF PHARMACOLOGY
2022Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx NATURE COMMUNICATIONS
2021Intracellular NAD + Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation FRONTIERS IN IMMUNOLOGY
2021Exacerbation of Mycobacterium avium pulmonary infection by comorbid allergic asthma is associated with diminished mycobacterium-specific Th17 responses VIRULENCE
2021Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu FRONTIERS IN IMMUNOLOGY
2021Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain NATURE COMMUNICATIONS
2020Dysregulation of sonic hedgehog signaling causes hearing loss in ciliopathy mouse models ELIFE
2020Sequence-specific prediction of the efficiencies of adenine and cytosine base editorsNATURE BIOTECHNOLOGY
2020Antigen-Specific IFN-γ/IL-17-Co-Producing CD4 + T-Cells Are the Determinants for Protective Efficacy of Tuberculosis Subunit Vaccine VACCINES
2020Toll-like receptor 4 signaling-mediated responses are critically engaged in optimal host protection against highly virulent Mycobacterium tuberculosis K infection VIRULENCE
2020Plant-Produced N-glycosylated Ag85A Exhibits Enhanced Vaccine Efficacy Against Mycobacterium tuberculosis HN878 Through Balanced Multifunctional Th1 T Cell Immunity VACCINES
2020Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosisVACCINE
2018Deep learning improves prediction of CRISPR-Cpf1 guide RNA activityNATURE BIOTECHNOLOGY