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Yonsei Advanced Medical Science Research and Education (첨단의과학교육연구단)

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Highly Cited Articles

Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Kim, Hui Kwon ; Min, Seonwoo ; Song, Myungjae ; Jung, Soobin ; Choi, Jae Woo ... Nature Biotechnology, Vol.36(3) : 239-241, 2018-03

Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Kim, Hui Kwon ; Min, Seonwoo ; Song, Myungjae ; Jung, Soobin ; Choi, Jae Woo ... Nature Biotechnology, Vol.36(3) : 239-241, 2018-03

Sequence-specific prediction of the efficiencies of adenine and cytosine...

Myungjae Song ; Hui Kwon Kim ; Sungtae Lee ; Younggwang Kim ; Sang-Yeon Seo ;... NATURE BIOTECHNOLOGY, Vol.38(9) : 1037-1043, 2020-09
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Issue DateTitleJournal Title
2026Enhanced tuberculosis control via leveraging dendritic cell-mediated Th1 responses in preventive and immunotherapeutic vaccine strategies JOURNAL OF ADVANCED RESEARCH
2026An ESAT-6-convergent prime-boost vaccination combining recombinant BCG expressing Mycobacterium marinum ESX-1 and ESAT-6/GLA-SE improves TB protection NPJ VACCINES
2026Exploring Host-driven Immunopathological Factors Developing Severe Tuberculosis: Insights from Comparative Mouse Models International Journal of Biological Sciences
2025Adjunctive beneficial effect of c-di-GMP, a STING agonist, in enhancing protective efficacy of TLR4-adjuvanted tuberculosis subunit vaccine formulations JOURNAL OF BIOMEDICAL SCIENCE
2024Permissive lung neutrophils facilitate tuberculosis immunopathogenesis in male phagocyte NADPH oxidase-deficient micePLOS PATHOGENS
2024Immunogenicity and protective efficacy of RipA, a peptidoglycan hydrolase, against<i> Mycobacterium</i><i> tuberculosis</i> Beijing outbreak strainsVACCINE
2024Deep learning models to predict the editing efficiencies and outcomes of diverse base editorsNature Biotechnology
2024BCG-booster vaccination with HSP90-ESAT-6-HspX-RipA multivalent subunit vaccine confers durable protection against hypervirulent Mtb in miceNPJ VACCINES
2024Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axisEXPERIMENTAL AND MOLECULAR MEDICINE
2023Importance of adjuvant selection in tuberculosis vaccine development: Exploring basic mechanisms and clinical implicationsVACCINE: X
2023Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9sNATURE METHODS
2023Protective Efficacy and Immunogenicity of Rv0351/Rv3628 Subunit Vaccine Formulated in Different Adjuvants Against Mycobacterium tuberculosis InfectionImmune Network
2023Hedgehog signaling regulates Wolffian duct development through the primary cilium(dagger)Biology of Reproduction
2022Vaccination inducing durable and robust antigen-specific Th1/Th17 immune responses contributes to prophylactic protection against Mycobacterium avium infection but is ineffective as an adjunct to antibiotic treatment in chronic diseaseVirulence
2022Tissue-specific requirement of sodium channel and clathrin linker 1 (Sclt1) for ciliogenesis during limb developmentFrontiers in Cell and Developmental Biology
2022Novel Antibacterial Activity of Febuxostat, an FDA-Approved Antigout Drug against Mycobacterium tuberculosis InfectionANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2022BCG Delta BCG1419c increased memory CD8(+) T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosisSCIENTIFIC REPORTS
2022Host-directed anti-mycobacterial activity of colchicine, an anti-gout drug, via strengthened host innate resistance reinforced by the IL-1 beta/PGE(2) axisBritish Journal of Pharmacology
2022Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influxNature Communications
2021Intracellular NAD(+) Depletion Confers a Priming Signal for NLRP3 Inflammasome ActivationFrontiers in Immunology
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