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One-year clinical outcomes of coronary chronic total occlusion intervention in patients with acute coronary syndrome versus stable angina: from the Korean chronic total occlusion registry

Authors
 Jah Yeon Choi  ;  Byoung Geol Choi  ;  Seung-Woon Rha  ;  Ahmed Mashaly  ;  Kareem Abdelshafi  ;  Cheol Ung Choi  ;  Cheol Woong Yu  ;  Hyeon-Cheol Gwon  ;  In-Ho Chae  ;  Hyo-Soo Kim  ;  Hun Sik Park  ;  Seung-Hwan Lee  ;  Moo-Hyun Kim  ;  Seung-Ho Hur  ;  Yangsoo Jang 
Citation
 CORONARY ARTERY DISEASE, Vol.31(5) : 430-437, 2020-08 
Journal Title
CORONARY ARTERY DISEASE
ISSN
 0954-6928 
Issue Date
2020-08
Abstract
Background: Chronic total occlusion intervention remains challenging and detailed real-world data on the safety and efficacy of which are limited. This study sought to determine whether there are differences in the 1-year clinical outcomes between chronic total occlusion patients with acute coronary syndrome and stable angina following chronic total occlusion intervention.

Patients and methods: Data from the Korean chronic total occlusion registry were collected from May 2003 to September 2012, and a total of 3268 patients who underwent chronic total occlusion intervention were enrolled. Cardiovascular outcomes up to 12 months in the acute coronary syndrome group were compared with stable angina group.

Results: The acute coronary syndrome group consisted of 1657 patients, and stable angina group consisted of 1264 patients. In the acute coronary syndrome group, patients with successful chronic total occlusion intervention had a lower incidence of total death and cardiac death compared to patients with failed intervention. However, there were no significant differences in cardiovascular events in the stable angina group. The successful chronic total occlusion intervention was a significant prognostic factor for lower total death (P = 0.006, hazard ratio = 0.46) and cardiac death (P = 0.003, hazard ratio = 0.36) within acute coronary syndrome group. On the other hand, successful chronic total occlusion intervention was not a prognostic factor for cardiovascular events within stable angina group.

Conclusions: Successful chronic total occlusion intervention in acute coronary syndrome patients was associated with a lower incidence of cardiovascular outcome compared to patients with failed chronic total occlusion intervention.
Full Text
https://journals.lww.com/coronary-artery/Fulltext/2020/08000/One_year_clinical_outcomes_of_coronary_chronic.5.aspx
DOI
10.1097/MCA.0000000000000880
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Plastic and Reconstructive Surgery (성형외과학교실) > 1. Journal Papers
Yonsei Authors
Baek, Wooyeol(백우열) ORCID logo https://orcid.org/0000-0002-6638-4110
Suh, Young Chul(서영철)
Lee, Won Jai(이원재) ORCID logo https://orcid.org/0000-0003-3056-0503
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Hong, Jong Won(홍종원) ORCID logo https://orcid.org/0000-0002-7762-0940
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184955
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