0 8

Cited 0 times in

Detailed evaluation of Mobius3D dose calculation accuracy for volumetric-modulated arc therapy

Authors
 Jihun Kim  ;  Min Cheol Han  ;  Eungman Lee  ;  Kwangwoo Park  ;  Kyung Hwan Chang  ;  Dong Wook Kim  ;  Jin Sung Kim  ;  Chae-Seon Hong 
Citation
 PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, Vol.74 : 125-132, 2020-06 
Journal Title
 PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS 
ISSN
 1120-1797 
Issue Date
2020-06
Keywords
Accuracy evaluation ; Mobius3D ; Multileaf collimator modeling ; Patient-specific quality assurance
Abstract
Purpose: To perform a detailed evaluation of dose calculation accuracy and clinical feasibility of Mobius3D. Of particular importance, multileaf collimator (MLC) modeling accuracy in the Mobius3D dose calculation algorithm was investigated. Methods: Mobius3D was fully commissioned by following the vendor-suggested procedures, including dosimetric leaf gap (DLG) optimization. The DLG optimization determined an optimal DLG correction factor which minimized the average difference between calculated and measured doses for 13 patient volumetric-modulated arc therapy (VMAT) plans. Two sets of step-and-shoot plans were created to examine MLC and off-axis open fields modeling accuracy of the Mobius3D dose calculation algorithm: MLC test set and off-axis open field test set. The test plans were delivered to MapCHECK for the MLC tests and an ionization chamber for the off-axis open field test, and these measured doses were compared to Mobius3D-calculated doses. Results: The mean difference between the calculated and measured doses across the 13 VMAT plans was 0.6% with an optimal DLG correction factor of 1.0. The mean percentage of pixels passing gamma from a 3%/1 mm gamma analysis for the MLC test set was 43.5% across the MLC tests. For the off-axis open field tests, the Mobius3D-calculated dose for 1.5 cm square field was -4.6% lower than the chamber-measured dose. Conclusions: It was demonstrated that Mobius3D has dose calculation uncertainties for small fields and MLC tongue-and-groove design is not adequately taken into consideration in Mobius3D. Careful consideration of DLG correction factor, which affects the resulting dose distributions, is required when commissioning Mobius3D for patient-specific QA.
Full Text
https://www.sciencedirect.com/science/article/pii/S1120179720301289
DOI
10.1016/j.ejmp.2020.05.015
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Wook(김동욱) ORCID logo https://orcid.org/0000-0002-5819-9783
Kim, Jihun(김지훈) ORCID logo https://orcid.org/0000-0003-4856-6305
Kim, Jinsung(김진성) ORCID logo https://orcid.org/0000-0003-1415-6471
Park, Kwang Woo(박광우) ORCID logo https://orcid.org/0000-0002-9843-7985
Chang, Kyung Hwan(장경환)
Han, Min Cheol(한민철)
Hong, Chae-Seon(홍채선) ORCID logo https://orcid.org/0000-0001-9120-6132
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/179416
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links