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성견 열개형 수평 결손부에서 Calcium Sulfate 차단막이 치주조직 치유에 미치는 영향

Other Titles
 The Effects of Calcium sulfate Membrane on the Periodontal Wound Repair of Horizontal Dehiscence defects in Dogs 
Authors
 최성호  ;  조규성  ;  문익상  ;  채중규  ;  김종관 
Citation
 Journal of Korean Academy of Periodontology (대한치주과학회지), Vol.27(1) : 249-262, 1997 
Journal Title
Journal of Korean Academy of Periodontology(대한치주과학회지)
ISSN
 0250-3352 
Issue Date
1997
Keywords
Calcium sulfate ; Membrane ; Wound repair ; Dehiscence defects
Abstract
The present study investigates the effects of calcium sulfate graft on the periodontal healing in intrabony periodontal defects of dogs. Following the general anesthesia with 30mg/kg pentobarbital injected intravenously, the first premolar was extracted and full-thickness periodontal flap was elevated from the second premolar to the fourth premolar. The portion of premolars coronal to the alveolar crest was removed and mesial and distal roots were separated. Exposed root canals were sealed with Caviton and covered completely with flaps sutured.

Following the healing period of 12 weeks, the surgical sited were uncovered and 4×4mm intrabony defects were surgically created. Those defects with calcium sulfate graft following the root planing was designated as the test sites and those with flap surgery-only were designated as control sites. The animals were sacrificed after 8 weeks and the healing was histologically analyzed. The results were as follows.

1. No foreign body reaction or inflammation were observed in either groups. Calcium sulfate was completely resorbed in the test sites.

2. New cementum was observed coronal to the notch in both groups. Connective tissue fibers were oriented parallel to the root surface in the controls. Connective tissues were formed in large amount in the sites.

3. Test sites showed marked amount of new bone formation while the control sites showed minimal bone gain.

4. Root resorption was observed in coronal portions of th control sites. The results suggest that calcium sulfate is a biocompatible graft material with a potential for new bone and cementum formation.
Files in This Item:
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Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Moon, Ik Sang(문익상)
Cho, Kyoo Sung(조규성) ORCID logo https://orcid.org/0000-0002-6777-5287
Chai, Jung Kyu(채중규)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/177922
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