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성견 1면 골결손부에서 Bioactive Glass가 치주조직 치유에 미치는 영향

Other Titles
 The effects of bioactive glass on the periodontal healing of 1-wall intrabony defects in dogs 
 박원영  ;  조규성  ;  채중규  ;  김종관  ;  최성호 
 Journal of Korean Academy of Periodontology (대한치주과학회지), Vol.28(1) : 145-160, 1998 
Journal Title
 Journal of Korean Academy of Periodontology (대한치주과학회지) 
Issue Date
The ultimate goal of periodontal therapy is the regeneration of periodontal tissue which has been lost due to destructive periodontal disease, and numerous kinds of materials and techniques have been developed to achieve this goal. Bone grafts include autografts, allografts, xenografts and synthetic grafts. Among the synthetic grafts, bioactive glass has been used in dentistry for more than ten years and Fetner reported improved new bone formation and more amount of new attachment after grafting PerioGlas, a kind of bioactive glass, in 2-wall defects of monkeys in 1994. It Is well known that 1-wall defects have less osteogenic potential and more epithelial migration, so we need to study the erect of bioactive glass in 1-wall dejects in dogs. The present study evaluates the effect of bioactive glass on the epithelial migration, alveolar bone regeneration, cementum formation and gingival connective tissue attachment in intrabony detects of dogs. Four millimeter deep and four millimeter wide 1-wall defects were surgically cheated in the mesial aspects of premolars. The test group received bioactive glass with a flap procedure and the control underwent flap procedure only. Histologic analysis after 8 weeks of healing revealed the following results : 1. The height of gingival margin was 1.30±0.73㎜ above CEJ in the control and 1.40 ±0.78㎜ in the test group. There was no statistically significant difference between the two group. 2. The length of epithelial growth (the distance from CEJ to the apical end of JE) was 1.74±0.47㎜ in the control and 1.12±0.36㎜ in the test group. These was a statistically significant difference between the two groups (P<0.01) 3. The length of new cementum was 2.06±0.73㎜ in the control and 2.62±0.37㎜ in the test group. There was no statistically significant difference between the two groups. 4. The length of new bone was 1.83±0.74mm in the control and 2.39±0.59mm in the test group. There was no statistically significant difference between the two groups. These results suggest that the use of bioactive glass 1-wall intrabony defects has significant effect on the prevention of junctional epithelium migration, but doesn't haute any significant effect on new bone and new cementum formation.
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2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Cho, Kyoo Sung(조규성) ORCID logo https://orcid.org/0000-0002-6777-5287
Chai, Jung Kyu(채중규)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
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