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Periodontal repair in intrabony defects treated with a calcium sulfate implant and calciumsulfate barrier

 Chong-Kwan Kim  ;  Jung-Kiu Chai  ;  Kyoo-Sung Cho  ;  Ik-Sang Moon  ;  Seong-Ho Choi  ;  John S. Sottosanti  ;  Ulf M.E. Wikesjö 
 JOURNAL OF PERIODONTOLOGY, Vol.69(12) : 1317-1324, 1998 
Journal Title
Issue Date
Adult ; Alveolar Bone Loss/pathology ; Alveolar Bone Loss/surgery* ; Bone Matrix/transplantation ; Bone Substitutes/therapeutic use* ; Bone Transplantation/methods* ; Calcium Sulfate/therapeutic use* ; Female ; Follow-Up Studies ; Freeze Drying ; Gingivoplasty ; Guided Tissue Regeneration, Periodontal/methods* ; Humans ; Male ; Membranes, Artificial* ; Middle Aged ; Periodontal Attachment Loss/pathology ; Periodontal Attachment Loss/surgery ; Periodontal Pocket/pathology ; Periodontal Pocket/surgery ; Surgical Flaps ; Transplantation, Homologous ; Treatment Outcome
THIS RANDOMIZED, CONTROLLED, CLINICAL STUDY was designed to evaluate outcome following surgical implantation of an allogeneic, freeze-dried, demineralized bone matrix-calcium sulfate (DBM+CS) composite with a CS barrier in intrabony periodontal defects. Twenty-six patients contributing 26 deep intrabony defects completed the study. Thirteen patients received the DBM+CS implant. Thirteen patients received gingival flap surgery alone (GFS; control). Clinical outcome was assessed at 6 and 12 months postsurgery. At 12 months postsurgery, probing depth (PD) reduction (mean +/-SD) for the DBM+CS and GFS group was to 4.3+/-0.5 and 3.0+/-1.3 mm; clinical attachment gain was to 2.9+/-0.8 and 1.7+/-1.5 mm; and probing bone level gain was to 2.9+/-1.4 and 1.2+/-1.2 mm, respectively. There were no apparent differences between evaluations at 6 and 12 months postsurgery. Clinical improvements were significantly different from presurgery for both groups at both observation intervals (P < 0.01). There were no significant differences between groups in PD reduction and clinical attachment gain. Probing bone level gain was significantly greater in the DBM+CS group compared to controls (P < 0.05). In summary, surgical implantation of DBM+CS with a CS barrier resulted in reduced PD and improved attachment levels comparable to that achieved by gingival flap surgery alone. However, gain in probing bone levels in deep intrabony periodontal pockets assessed by clinical parameters was greater than that observed by gingival flap surgery alone. These changes were noted at both 6 and 12 months after surgery. This regenerative technique needs further biologic evaluation before being generally accepted.
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2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Moon, Ik Sang(문익상)
Cho, Kyoo Sung(조규성) ORCID logo https://orcid.org/0000-0002-6777-5287
Chai, Jung Kyu(채중규)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
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