Breast ; Biopsy ; Ultrasound guidance ; Breast cancer diagnosis
Abstract
Purpose: To determine the diagnostic accuracy, underestimation rate and false negative rate of
sonographically guided core needle biopsy for breast lesions.
Materials and Methods: We included 1,110 breast lesions from 966 patients who had undergone
sonographically guided 14-gauge core needle biopsies between January 2018 and December
2018. The sonographic BI-RADSⓇ category of breast lesions and the pathologic results of core
needle biopsies were reviewed and correlated with that of surgery or vacuum-assisted biopsy,
or >1year follow-up. The positive predictive value for each BI-RADSⓇ category, sensitivity,
underestimation rate and false negative rate of core needle biopsy were evaluated.
Results: Of the 1,110 core biopsy lesions, benign pathology was found in 37.6%, high-risk results
in 18.2%, and malignant results in 44.2%. The positive predictive values for each sonographic
category were as follows: 5% in category 3; 19.1% in category 4a; 74.6% in category 4b; 93.7% in
category 4c and 99.5% in category 5. The sensitivity of core needle biopsy was 93.7% (491/524).
The underestimation rate was 14.4% (29/202) for high-risk and 42.4% (39/92) for ductal
carcinoma in situ. The false negative rate was 1.0% (4/417).
Conclusion: Sonographically guided core needle biopsy for 2018 year in our hospital was accurate
diagnostic tool for evaluating breast lesion.