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수용성 Periodontitis-Medical Gel이 치은염, 치주염에 미치는 영향

Other Titles
 A Clinical Study of the Effect of Periodontitis-Medical Gel on Human Gingivitis and Periodontitis 
Authors
 채중규  ;  최재성  ;  박지숙  ;  서종진  ;  최성호  ;  조규성  ;  김종관 
Citation
 Journal of Korean Academy of Periodontology (대한치주과학회지), Vol.30(1) : 11-25, 2000 
Journal Title
 Journal of Korean Academy of Periodontology (대한치주과학회지) 
ISSN
 0250-3352 
Issue Date
2000
MeSH
Allantoin ; Burns ; Calculi ; Cetylpyridinium ; Gingivitis* ; Glycyrrhizic Acid ; Hand ; Hemorrhage ; Humans* ; Nausea ; Periodontal Index ; Periodontitis* ; Sensation ; Suppuration ; Surveys and Questionnaires
Keywords
Dentheth® ; periodontitis-medical gel ; Dipotassium glycyrrhizinate ; Allantoin ; Hinokitiol ; Cetylpyridinium chloride
Abstract
The purpose of this study was to evaluate the clinical effects of Dipotassium glycyrrhizinate, Allantoin, Hinokitiol, Cetylpyridinium chloride containing gel(Dentheth®) on periodontitis. 41 patients with sites having pocket depth of 4-6mm were selected for the study. We classified 2 groups which consisted of 21 patients in the test group(exp.) and 20 patients in the control(placebo) respectively. Following a baseline examination, plaque and calculus were removed and then the experimental gel were handed out to the patients and topical application regimens were initiated. During the 4-week experimental period, pocket depth, bleeding on probing, gingival index, plaque index as a clinical parameters were measured in the baseline, 2 weeks, 4 weeks respectively. A questionnaire was delivered to each patients in 2 weeks, 4 weeks respectively. The results were as follows: 1.Probing pocket depth showed a significant difference in the Exp. group compared with the control group in the changes from baseline to 2 weeks(p<0.05), but there was no significant difference between the groups in the changes from baseline to 4 weeks, from 2 weeks to 4 weeks(p<0.05). 2.The Exp. group showed a significant difference compared with the control group in the changes from baseline to 2 weeks, from baseline to 4 weeks, from 2 weeks to 4 weeks in bleeding on probing(p<0.05). 3. The gingival index showed a significant difference compared with the control group in the changes from baseline to 2 weeks, from baseline to 4 weeks, from 2 weeks to 4 weeks after 4 weeks use of a gel(p<0.05). 4.The plaque index showed a significant difference in the Exp. group compared with the control group in the changes from baseline to 2 weeks(p<0.05), but there was no significant difference between the groups in the changes from baseline to 4 weeks, from 2 weeks to 4 weeks(p<0.05). 5.A questionnaire was consisted of 5 kinds as to bleeding, pus discharge, pain, burning sensation, patient's satisfaction and all of the questions showed a significant difference compared with the control group in the changes from 2 weeks to 4 weeks(p<0.05). 6.During the 4-week experimental period, important side-effects were not finded out, but each groups had one patient appealed nausea or discomfort respectively. These results indicate that application of periodontitis-medical gel was useful as an additional aid of mechanical treatment.
Files in This Item:
T200003443.pdf Download
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Cho, Kyoo Sung(조규성) ORCID logo https://orcid.org/0000-0002-6777-5287
Chai, Jung Kyu(채중규)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172386
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