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3가지 인공누액 점안 후 점탄성에 의한 눈물층 분포 비교

Other Titles
 The Comparison of Viscosity -dependent Distribution of Tear Film after Dropping of Three Artificial Tears 
Authors
 현준일  ;  김응권  ;  이재범 
Citation
 Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.41(3) : 607-612, 2000 
Journal Title
JOURNAL OF THE KOREAN OPHTHALMOLOGICAL SOCIETY(대한안과학회지)
ISSN
 0378-6471 
Issue Date
2000
Keywords
Artificial tear ; Dry eye ; Tear film thickness ; Viscosity
Abstract
We intended to evaluate the viscosity-dependent distribution of tear film after dropping of three artificial tears with different viscosity. We measured the corneal thickness including tear film thickness after dropping of Optagent[Povidon iodide 2%; viscosity: 1.5millimeter2/sec], Tears naturale free[hydroxypropyl methylcellulose 0.3%, dextran 0.1%;6.4 millimeter2/sec], Lacura [sodium hyaluronate 0.1%;4.6 millimeter2/sec]in 12 adult men and women without dry eye by optical beam scanning differential pachymetry of Orbscan topography. 1 minute after dropping, the thickness of 3 millimeter superior and inferior to center of cornea increased respectively 4.1 +/-0.4 micrometer, 0.4 +/-0.1micrometer[p=0.014]in Optagent, 2.4 +/-0.3 micrometer, 2.3 +/-0.2 micrometer[p=0.425]in Tears naturale free and 2.5 +/-0.5 micrometer, 2.0 +/-0.2 micrometer[p=0.126]in Lacure. 10 minute after dropping, the thickness of 3 millimeter superior and inferior to center of cornea increased respectively 2.7 +/-0.3 micrometer, 0.3 +/-0.1 micrometer[p=0.025]in Optagent, 1.7 +/-0.2 micrometer, 1.6 +/-0.2 micrometer[p=0.326]in Tears naturale free and 1.4 +/-0 .4 micrometer, 1.2 +/-0.2 micrometer[p=0.237]in Lacura. In conclusion, the artificial tears with relatively high viscosity dstributed evenly along the corneal surface after dropping, but those with relatively low viscosity distributed mainly superior to center of cornea with statistical significance. So when treating of corneal lesion in dry eye, we think that artificial tears with proper viscosity will be needed according to the location of the lesion.
Files in This Item:
T200001282.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172241
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