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진행성 뇌졸중에서 확산 강조영상의 유요성 : 임상증상과의 비교

Other Titles
 Usefulness of Diffusion-Weighted Image in the Evolving Stroke : Correlation with Clinical Findings 
 김현숙  ;  김동익  ;  윤평호  ;  이승익  ;  이병인  ;  서범천  ;  윤용규 
 Journal of the Korean Radiologist Society (대한방사선의학회지), Vol.43(3) : 273-279, 2000 
Journal Title
Journal of the Korean Radiologist Society(대한방사선의학회지)
Issue Date
Brain ; ischemia Magnetic resonance (MR) ; diffusion study
Purpose: To determine the usefulness of repeat diffusion-weighted imaging (DWI) during the acute ischemic stroke stage for the prediction of evolving stroke and clinical course.
Materials and Methods: Fifteen patients with acute ischemic stroke in MCA territory [<24 hours, 5 patients; >24 hours, 10 patients; M:F=9:6; age 28-75 (mean, 61) years] were involved in this prospective study. All patients underwent initial DWI, follow-up DWI (within two weeks of the first attack) and T2WI (2-5 months later to assess final infarction territory). The National Institute of Health Stroke Scale (NIHSS) was used for clinical evaluation.‘ Evolving stroke’was defined as progression of NIHSS after admission. For statistical analysis,
Fisher’s exact test was used and a p value < 0.05 was considered significant.
Results: In six patients (40%), the diagnosis was evolving stroke. In four of these (67%), follow-up DWI showed that the infarction territory was more extensive. Evolving stroke occurred 24-72 hours after the onset of symptoms. DWI obtained 72 hours after onset showed that one patient had developed new infarction. Patients in whom enlarged infarction territory was seen on follow-up DWI showed progression of NIHSS within three days of onset, while those in whom follow-up DWI demonstrated no change showed an improved NIHSS (p < 0.05). Those who underwent initial DWI within 24 hours of onset showed larger infarction territory on follow-up DWI than those who underwent initial DWI later than this (p < 0.05).
Conclusion: Repeat DWI during the acute ischemic stroke stage might be useful for the evaluation of evolving stroke.
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1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Ik(김동익)
Lee, Byung In(이병인)
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