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Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging

Authors
 Young Bin Ji  ;  Jung Min Kim  ;  Young Han Lee  ;  Yuna Choi  ;  Da Hee Kim  ;  Yong-Min Huh  ;  Seung Jae Oh  ;  Yoon Woo Koh  ;  Jin-Suck Suh 
Citation
 JOURNAL OF INFRARED MILLIMETER AND TERAHERTZ WAVES, Vol.40(2) : 247-256, 2019 
Journal Title
 JOURNAL OF INFRARED MILLIMETER AND TERAHERTZ WAVES 
ISSN
 1866-6892 
Issue Date
2019
Keywords
Terahertz imaging ; Medical and biological imaging ; Terahertz spectroscopy ; Tissue diagnostics ; Optical diagnostics for medicine
Abstract
We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.
Full Text
https://link.springer.com/article/10.1007/s10762-018-0562-7
DOI
10.1007/s10762-018-0562-7
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
5. Research Institutes (연구소) > Institute for Medical Convergence (연의-생공연 메디컬융합연구소) > 1. Journal Papers
Yonsei Authors
Kho, Yoon Woo(고윤우)
Kim, Da Hee(김다희) ORCID logo https://orcid.org/0000-0001-7286-1334
Kim, Jung Min(김정민)
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Oh, Seung Jae(오승재)
Lee, Young Han(이영한) ORCID logo https://orcid.org/0000-0002-5602-391X
Ji, Young Bin(지영빈)
Huh, Yong Min(허용민) ORCID logo https://orcid.org/0000-0002-9831-4475
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/169931
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