2021 | Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain
| NATURE COMMUNICATIONS |
2022 | Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair
| STEM CELL RESEARCH |
2016 | Generation of ΔF508-CFTR T84 cell lines by CRISPR/Cas9-mediated genome editing | BIOTECHNOLOGY LETTERS |
2020 | Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer | CELL DEATH AND DIFFERENTIATION |
2014 | Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells.
| JOURNAL OF VIROLOGY |
2016 | Heroes of peer review: Hyongbum (Henry) Kim
| GENOME BIOLOGY |
2020 | High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells | NATURE BIOMEDICAL ENGINEERING |
2022 | High-throughput functional evaluation of human cancer-associated mutations using base editors | NATURE BIOTECHNOLOGY |
2021 | Improving CRISPR tools by elucidating DNA repair | NATURE BIOTECHNOLOGY |
2016 | In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia
| MOLECULAR THERAPY |
2023 | In vivo application of base and prime editing to treat inherited retinal diseases | PROGRESS IN RETINAL AND EYE RESEARCH |
2018 | In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
2017 | In vivo high-throughput profiling of CRISPR-Cpf1 activity | NATURE METHODS |
2022 | In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model
| THERANOSTICS |
2019 | LIN28A loss of function is associated with Parkinson's disease pathogenesis
| EMBO JOURNAL |
2022 | Magnetogenetics with Piezo1 Mechanosensitive Ion Channel for CRISPR Gene Editing | NANO LETTERS |
2023 | Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9s | NATURE METHODS |
2018 | Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption | NUCLEIC ACIDS RESEARCH |
2021 | Predicting the efficiency of prime editing guide RNAs in human cells | NATURE BIOTECHNOLOGY |
2023 | Prediction of efficiencies for diverse prime editing systems in multiple cell types | CELL |
2020 | Prediction of the sequence-specific cleavage activity of Cas9 variants | NATURE BIOTECHNOLOGY |
2019 | Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis
| Molecular Therapy Oncolytics |
2017 | RanBPM: a potential therapeutic target for modulating diverse physiological disorders | DRUG DISCOVERY TODAY |
2015 | Recent developments and clinical studies utilizing engineered zinc finger nuclease technology | CELLULAR AND MOLECULAR LIFE SCIENCES |
2021 | Recording of elapsed time and temporal information about biological events using Cas9 | CELL |
2016 | Regulation of pluripotency and differentiation by deubiquitinating enzymes. | CELL DEATH AND DIFFERENTIATION |
2015 | Rh D blood group conversion using transcription activator-like effector nucleases
| NATURE COMMUNICATIONS |
2020 | Sequence-specific prediction of the efficiencies of adenine and cytosine base editors | NATURE BIOTECHNOLOGY |
2023 | Sniper2L is a high-fidelity Cas9 variant with high activity | NATURE CHEMICAL BIOLOGY |
2017 | Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia | AMERICAN JOURNAL OF HUMAN GENETICS |
2019 | SpCas9 activity prediction by DeepSpCas9, a deep learning-based model with high generalization performance
| Science Advances |
2017 | Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction
| STEM CELLS TRANSLATIONAL MEDICINE |
2018 | Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth
| GENOME RESEARCH |
2019 | Therapeutic application of the CRISPR system: current issues and new prospects | Human Genetics |