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Can the integrity of the corticospinal tract predict the long-term motor outcome in poststroke hemiplegic patients?

DC FieldValueLanguage
dc.contributor.author경성현-
dc.contributor.author김덕용-
dc.contributor.author김용욱-
dc.contributor.author이승구-
dc.date.accessioned2018-08-28T17:06:10Z-
dc.date.available2018-08-28T17:06:10Z-
dc.date.issued2018-
dc.identifier.issn0959-4965-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/162256-
dc.description.abstractThis study aimed to investigate the long-term motor outcome according to early diffusion tensor tractography findings for the affected corticospinal tract (CST) in poststroke hemiplegic patients. A total of 48 supratentorial subacute patients after stroke were enrolled, who had a brain MRI scan within 6 weeks from onset, and no stroke recurrence reported within the 2-year follow-up period. Diffusion tensor images were obtained and CSTs were reconstructed. The participants were classified into three groups: type A, the CST originating from the primary motor cortex was preserved around the lesion area; type B, the CST was similar to type A, except that the fiber originated from the area adjacent to the primary motor cortex; and type C, the CST was interrupted or not shown. Motor functions using Fugl-Meyer Motor Assessment (FMA), the Box and Block Test (BBT), and Functional Ambulation Category, and cognitive function using Mini-Mental Status Examination (MMSE) were measured at baseline and at 2 years from stroke onset. Changes in FMA and BBT were significantly different according to diffusion tensor tractography type at follow-up (P<0.05), but Functional Ambulation Category and Mini-Mental Status Examination were not. In post-hoc analysis, groups A and B showed greater significant improvements on the BBT and on the upper FMA subscale (shoulder/elbow, wrist, and hand) compared with group C (corrected P<0.05), but did not on lower FMA. This study showed the importance of CST integrity for stoke motor recovery. The early integrity of the CST may be useful in predicting long-term motor outcomes, specifically with motor recovery of the upper extremity and hand function.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfNeuroreport-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleCan the integrity of the corticospinal tract predict the long-term motor outcome in poststroke hemiplegic patients?-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Life Science-
dc.contributor.googleauthorAe Ryoung Kim-
dc.contributor.googleauthorDae Hyun Kim-
dc.contributor.googleauthorSo Young Park-
dc.contributor.googleauthorSunghyon Kyeong-
dc.contributor.googleauthorYong Wook Kim-
dc.contributor.googleauthorSeung Koo Lee-
dc.contributor.googleauthorDeog Young Kim-
dc.identifier.doi10.1097/wnr.0000000000000994-
dc.contributor.localIdA04506-
dc.contributor.localIdA00375-
dc.contributor.localIdA00750-
dc.contributor.localIdA02912-
dc.relation.journalcodeJ02361-
dc.identifier.eissn1473-558X-
dc.identifier.pmid29481524-
dc.identifier.urlhttps://insights.ovid.com/crossref?an=00001756-201804010-00003-
dc.contributor.alternativeNameKyeong, Sung Hyon-
dc.contributor.alternativeNameKim, Deog Young-
dc.contributor.alternativeNameKim, Yong Wook-
dc.contributor.alternativeNameLee, Seung Koo-
dc.contributor.affiliatedAuthorKyeong, Sung Hyon-
dc.contributor.affiliatedAuthorKim, Deog Young-
dc.contributor.affiliatedAuthorKim, Yong Wook-
dc.contributor.affiliatedAuthorLee, Seung Koo-
dc.citation.volume29-
dc.citation.number6-
dc.citation.startPage453-
dc.citation.endPage458-
dc.identifier.bibliographicCitationNeuroreport, Vol.29(6) : 453-458, 2018-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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